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见血封喉的高质量染色体水平基因组组装。

A high-quality chromosome-level genome assembly of Antiaris toxicaria.

作者信息

Huang Weicheng, Xiang Jiaxin, Ding Yamei, Liu Wanzhen, Fang Ni, Xiong Yongmei, Dai Seping, Yu Hui

机构信息

Key Laboratory of National Forestry and Grassland Administration on Plant Conservation and Utilization in Southern China, South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou, 510650, China.

Department of Computer Science, Hong Kong Baptist University, Kowloon, 999077, Hong Kong, China.

出版信息

BMC Genom Data. 2025 Mar 24;26(1):21. doi: 10.1186/s12863-025-01309-2.

Abstract

OBJECTIVES

Antiaris toxicaria is a tall tree belonging to the Moraceae family, known for its medicinal value. Its latex contains various cardiac glycosides, which hold significant research and potential application value. However, the lack of genomic resources for A. toxicaria currently hinders molecular genetic studies on its medicinal components. For its effective conservation and elucidation of the distinctive genetic traits of and medical components, we present its chromosome-level genome assembly.

DATA DESCRIPTION

Here, we assembled two haplotypes of A. toxicaria, including a 671.73-Mb HapA subgenome containing 27,213 genes and a 666.41-Mb HapB subgenome containing 28,840 genes. Their contig N50 sizes were 90.18 and 90.29 Mb, respectively. The transposable elements represented 61.15% and 64.13% of the total assembled genome in HapA and HapB subgenome, respectively. A total of 27,213 and 28,840 genes were predicted in the two haplotypes. Hopefully, this chromosome-level genome of A. toxicaria will provide a valuable resource to enhance understanding of the biosynthesis of medicinal compounds.

摘要

目的

见血封喉是一种属于桑科的高大树木,以其药用价值而闻名。其乳胶含有多种强心苷,具有重要的研究和潜在应用价值。然而,目前见血封喉缺乏基因组资源,这阻碍了对其药用成分的分子遗传学研究。为了对其进行有效保护并阐明其独特的遗传特征和药用成分,我们展示了其染色体水平的基因组组装。

数据描述

在此,我们组装了见血封喉的两个单倍型,包括一个含有27213个基因的671.73 Mb的HapA亚基因组和一个含有28840个基因的666.41 Mb的HapB亚基因组。它们的重叠群N50大小分别为90.18 Mb和90.29 Mb。转座元件分别占HapA和HapB亚基因组总组装基因组的61.15%和64.13%。在这两个单倍型中总共预测到27213个和28840个基因。有望,这个见血封喉的染色体水平基因组将为增进对药用化合物生物合成的理解提供宝贵资源。

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