• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脂肪、炎症与超声:肥胖对儿童关节炎症的影响。

Fat, flames and ultrasounds: the effects of obesity on pediatric joint inflammation.

作者信息

Di Ludovico Armando, Mascioli Ilaria, Bella Saverio La, Grassi Giovanni, Mastromauro Concetta, Breda Luciana, Chiarelli Francesco, Musolino Anna Maria, Giannini Cosimo, Corsello Antonio

机构信息

Department of Pediatrics, University of Chieti "G. D'Annunzio", Chieti, Italy, Via dei Vestini, Chieti, Italy.

UOC Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, Genova, Italy.

出版信息

Ital J Pediatr. 2025 Mar 24;51(1):96. doi: 10.1186/s13052-025-01937-5.

DOI:10.1186/s13052-025-01937-5
PMID:40128829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11934683/
Abstract

The association between childhood obesity and the early appearance of joint degeneration, particularly in the infrapatellar "Hoffa's" fat pad, highlights the importance of early diagnosis and treatment. The purpose of this review is to describe the role of ultrasound imaging as a first-line imaging tool for the early detection, prevention, and follow-up of degenerative structural changes in children's joints. By combining ultrasound findings with clinical assessments and indices, healthcare providers can gain a more comprehensive understanding of obesity-related joint alterations. This integrative approach enables early therapeutic interventions, improving outcomes for affected children. Proactive management of pediatric obesity will not only improve the long-term outcomes of obesity-related joint disorders but also reduce the burden of related complications, such as osteoarthritis, in adulthood.

摘要

儿童肥胖与关节退变的早期出现之间的关联,尤其是在髌下“霍法氏”脂肪垫处,凸显了早期诊断和治疗的重要性。本综述的目的是描述超声成像作为一线成像工具在儿童关节退行性结构变化的早期检测、预防和随访中的作用。通过将超声检查结果与临床评估和指标相结合,医疗保健提供者可以更全面地了解与肥胖相关的关节改变。这种综合方法能够实现早期治疗干预,改善受影响儿童的预后。积极管理儿童肥胖不仅将改善肥胖相关关节疾病的长期预后,还将减轻成年期相关并发症(如骨关节炎)的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/0e7989584f30/13052_2025_1937_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/17cc8e0e573c/13052_2025_1937_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/87da6e43ee8a/13052_2025_1937_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/0e7989584f30/13052_2025_1937_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/17cc8e0e573c/13052_2025_1937_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/87da6e43ee8a/13052_2025_1937_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cbb/11934683/0e7989584f30/13052_2025_1937_Fig3_HTML.jpg

相似文献

1
Fat, flames and ultrasounds: the effects of obesity on pediatric joint inflammation.脂肪、炎症与超声:肥胖对儿童关节炎症的影响。
Ital J Pediatr. 2025 Mar 24;51(1):96. doi: 10.1186/s13052-025-01937-5.
2
Comparison of the effectiveness of intra-infrapatellar fat pad and intra-articular glucocorticoid injection in knee osteoarthritis patients with Hoffa's synovitis: protocol for a multicentre randomised controlled trial.髌下脂肪垫内注射与关节腔内注射糖皮质激素治疗合并Hoffa滑膜炎的膝骨关节炎患者的疗效比较:一项多中心随机对照试验方案
BMJ Open. 2025 Jan 28;15(1):e087785. doi: 10.1136/bmjopen-2024-087785.
3
Magnetic resonance imaging of Hoffa's fat pad and relevance for osteoarthritis research: a narrative review.霍法脂肪垫的磁共振成像及其在骨关节炎研究中的相关性:一项叙述性综述
Osteoarthritis Cartilage. 2016 Mar;24(3):383-97. doi: 10.1016/j.joca.2015.09.018. Epub 2015 Oct 9.
4
Hoffa's fat pad thickness: a measurement method with sagittal MRI sequences.霍法脂肪垫厚度:一种利用矢状面MRI序列的测量方法。
Radiol Med. 2021 Jun;126(6):886-893. doi: 10.1007/s11547-021-01345-9. Epub 2021 Mar 27.
5
Imaging findings of Hoffa's fat pad herniation.霍法脂肪垫疝的影像学表现。
Pediatr Radiol. 2016 Apr;46(4):508-12. doi: 10.1007/s00247-015-3515-5. Epub 2015 Dec 9.
6
[Hoffa's disease of the adipose pad: magnetic resonance versus surgical findings].[脂肪垫的霍法氏病:磁共振成像与手术结果对比]
Radiol Med. 1998 Apr;95(4):278-85.
7
Presence of a t(12;18)(q14;q21) Chromosome Translocation and Fusion of the Genes for High-mobility Group AT-Hook 2 () and WNT Inhibitory Factor 1 () in Infrapatellar Fat Pad Cells from a Patient With Hoffa's Disease.患者 Hoffa 病髌下脂肪垫细胞中存在 t(12;18)(q14;q21) 染色体易位,以及高迁移率族 AT 钩蛋白 2()和 WNT 抑制因子 1()基因融合。
Cancer Genomics Proteomics. 2022 Sep-Oct;19(5):584-590. doi: 10.21873/cgp.20343.
8
A giant extrasynovial osteochondroma in the infrapatellar fat pad: end stage Hoffa's disease.髌下脂肪垫内巨大滑膜外骨软骨瘤:终末期霍法氏病
Arch Orthop Trauma Surg. 2008 May;128(5):515-9. doi: 10.1007/s00402-007-0397-5. Epub 2007 Jul 24.
9
A rare case of Hoffa's fat pad herniation in a young patient: dynamic ultrasound and MRI diagnosis.一例年轻患者 Hoffa 脂肪垫疝的罕见病例:动态超声和 MRI 诊断。
J Biol Regul Homeost Agents. 2018 Nov-Dec;32(6 Suppl. 1):77-81.
10
Hoffa's fat-pad inflammation in an HIV-positive patient.一名HIV阳性患者的霍法脂肪垫炎症
Radiol Case Rep. 2015 Nov 6;5(4):446. doi: 10.2484/rcr.v5i4.446. eCollection 2010.

本文引用的文献

1
The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis.髌下脂肪垫在炎症衰老、膝关节健康和骨关节炎中的作用
NPJ Aging. 2024 Jul 15;10(1):34. doi: 10.1038/s41514-024-00159-z.
2
Pathogenic Mechanisms and Therapeutic Approaches in Obesity-Related Knee Osteoarthritis.肥胖相关膝关节骨关节炎的发病机制与治疗方法
Biomedicines. 2023 Dec 20;12(1):9. doi: 10.3390/biomedicines12010009.
3
Utilizing MSK Ultrasound for Comprehensive Assessment of the Femoral Trochlea: A Game Changer in Sports Medicine.利用肌肉骨骼超声对股骨滑车进行全面评估:运动医学中的一项变革性技术。
Int J Sports Phys Ther. 2023 Dec 1;18(6):1376-1380. doi: 10.26603/001c.90038. eCollection 2023.
4
Association between infrapatellar fat pad ultrasound elasticity and anterior knee pain in patients with knee osteoarthritis.髌下脂肪垫超声弹性与膝骨关节炎患者前膝痛的相关性。
Sci Rep. 2023 Nov 16;13(1):20103. doi: 10.1038/s41598-023-47459-0.
5
The Effects of Ultrasound-Guided Intra-Articular Injections with Hyaluronic Acid and Corticosteroids in Patients with Hip Osteoarthritis: A Long-Term Real-World Analysis.超声引导下透明质酸和皮质类固醇关节腔内注射对髋骨关节炎患者的影响:一项长期真实世界分析
J Clin Med. 2023 Oct 18;12(20):6600. doi: 10.3390/jcm12206600.
6
Redefining Radiology: A Review of Artificial Intelligence Integration in Medical Imaging.重新定义放射学:医学成像中人工智能整合的综述
Diagnostics (Basel). 2023 Aug 25;13(17):2760. doi: 10.3390/diagnostics13172760.
7
Lifestyle and Pharmacological Interventions and Treatment Indications for the Management of Obesity in Children and Adolescents.儿童和青少年肥胖管理的生活方式及药物干预与治疗指征
Children (Basel). 2023 Jul 17;10(7):1230. doi: 10.3390/children10071230.
8
Ultrasound Evaluation of Knee Osteoarthritis.膝关节骨关节炎的超声评估
Cureus. 2023 May 18;15(5):e39188. doi: 10.7759/cureus.39188. eCollection 2023 May.
9
Predisposing factors for Hoffa's fat pad syndrome: a systematic review.霍法脂肪垫综合征的诱发因素:一项系统评价
Knee Surg Relat Res. 2023 Jun 9;35(1):17. doi: 10.1186/s43019-023-00192-4.
10
Adipose-derived stem cells and obesity: The spear and shield relationship.脂肪来源干细胞与肥胖:矛与盾的关系。
Genes Dis. 2021 Oct 2;10(1):175-186. doi: 10.1016/j.gendis.2021.09.004. eCollection 2023 Jan.