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影响姑息治疗可及性的因素:一项系统综述和荟萃分析。

Factors influencing accessibility of palliative care: a systematic review and meta-analysis.

作者信息

Shi Zhiyi, Du Mai, Zhu Shuqin, Lei Yang, Xu Qin, Li Weiying, Gu Wenwen, Zhao Ning, Chen Yi, Liu Wanting, Wang Haonan, Jiang Yucheng

机构信息

School of Nursing, Nanjing Medical University, Nanjing, China.

出版信息

BMC Palliat Care. 2025 Mar 24;24(1):80. doi: 10.1186/s12904-025-01704-7.

Abstract

BACKGROUND

Palliative care is essential for enhancing quality of life in patients with life-threatening illnesses. However, its accessibility remains inconsistent across populations and regions. This review systematically examines and quantifies factors influencing accessibility of palliative care.

METHODS

We conducted a comprehensive literature search in PubMed, Web of Science, CINAHL, Embase, the Cochrane Library, CNKI, Wanfang, and VIP databases, covering the period from January 2014 to July 2024. The search aimed to identify observational studies on factors influencing accessibility of palliative care. Keywords related to accessibility were derived from the five dimensions defined by Penchansky and Thomas: availability, accessibility, accommodation, affordability, and acceptability. Study quality was assessed using the Joanna Briggs Institute (JBI) tools, and a meta-analysis was conducted using Review Manager 5.3.

RESULTS

A total of 20 studies were included in the analysis, with 15 using a retrospective design with secondary data analysis, two employing a cross-sectional design, and three using a cohort design. There were no studies on availability, one study on accessibility, two studies on affordability, one study on accommodation, and sixteen studies on acceptability. The influencing factor for accessibility is geographic location. The influencing factors for affordability and accommodation are mainly demographic characteristics, including race, religion, and employment status. The most influential factors for acceptability are categorized as sociodemographic, healthcare service, disease-related factors. Meta-analysis results indicated that female gender (OR = 1.18, 95% CI: 1.14-1.23), higher income level (OR = 1.11, 95% CI: 1.08-1.14), and larger hospital bed capacity (OR = 1.22, 95% CI: 1.14-1.32) facilitated accessibility to palliative care (P < 0.05). Conversely, residing in rural areas (OR = 0.80, 95% CI: 0.67-0.95) and being of African descent (OR = 0.78, 95% CI: 0.68-0.90) were barriers to accessibility (P < 0.05).

CONCLUSIONS

This review highlights a relationship between key sociodemographic characteristics, healthcare service, disease-related factors and the accessibility of palliative care. However, the limited number of studies focusing on specific dimensions, such as availability, affordability, accessibility, and accommodation, creates gaps in understanding. Further research is needed to clarify the underlying mechanisms and potential causality of these associations. Recognizing the significant implications of limited accessibility of palliative care can help identify underserved populations and develop targeted interventions to improve the access to the service for these groups.

摘要

背景

姑息治疗对于提高危及生命疾病患者的生活质量至关重要。然而,其可及性在不同人群和地区之间仍存在差异。本综述系统地研究并量化了影响姑息治疗可及性的因素。

方法

我们在PubMed、Web of Science、CINAHL、Embase、Cochrane图书馆、中国知网、万方和维普数据库中进行了全面的文献检索,涵盖2014年1月至2024年7月期间。该检索旨在识别关于影响姑息治疗可及性因素的观察性研究。与可及性相关的关键词源自Penchansky和Thomas定义的五个维度:可获得性、可达性、适应性、可负担性和可接受性。使用乔安娜·布里格斯研究所(JBI)工具评估研究质量,并使用Review Manager 5.3进行荟萃分析。

结果

共有20项研究纳入分析,其中15项采用回顾性设计并进行二次数据分析,2项采用横断面设计,3项采用队列设计。关于可获得性方面没有研究,关于可达性方面有1项研究,关于可负担性方面有2项研究,关于适应性方面有1项研究,关于可接受性方面有16项研究。可达性的影响因素是地理位置。可负担性和适应性的影响因素主要是人口统计学特征,包括种族、宗教和就业状况。可接受性的最有影响因素分为社会人口学、医疗服务、疾病相关因素。荟萃分析结果表明,女性(OR = 1.18,95%CI:1.14 - 1.23)、较高收入水平(OR = 1.11,95%CI:1.08 - 1.14)和较大的医院床位容量(OR = 1.22,95%CI:1.14 - 1.32)有助于姑息治疗的可及性(P < 0.05)。相反,居住在农村地区(OR = 0.80,95%CI:0.67 - 0.95)和非洲裔(OR = 0.78,95%CI:0.68 - 0.90)是可及性的障碍(P < 0.05)。

结论

本综述强调了关键的社会人口学特征、医疗服务、疾病相关因素与姑息治疗可及性之间的关系。然而,关注可获得性、可负担性、可达性和适应性等特定维度的研究数量有限,导致在理解上存在差距。需要进一步研究以阐明这些关联的潜在机制和因果关系。认识到姑息治疗可及性有限的重大影响有助于识别服务不足的人群,并制定针对性干预措施以改善这些群体获得该服务的机会。

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