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超声引导下脉冲射频治疗颈源性头痛的疗效和安全性:一项聚焦于C1-2水平C2背根神经节的回顾性研究

Efficacy and safety of ultrasound-guided pulsed radiofrequency for cervicogenic headache: a retrospective study focusing on the C2 dorsal root ganglion at the C1-2 level.

作者信息

Jin Xing, Li Chenxi, Zhang Qingyu, Sun Ye, Qin Xiangzheng, Dong Zhiting, Jin Wenzhe, Li Kai

机构信息

Department of Pain, Yanbian University Hospital, 133000 Yanji, Jilin, China.

Department of Oral and Maxillofacial Oncology & Surgery, School/Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, 830054 Urumqi, Xinjiang Uygur Autonomous Region, China.

出版信息

J Oral Facial Pain Headache. 2025 Mar;39(1):112-118. doi: 10.22514/jofph.2025.010. Epub 2025 Mar 12.

DOI:10.22514/jofph.2025.010
PMID:40129428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11934735/
Abstract

BACKGROUND

This study evaluated the effectiveness and safety of ultrasound-guided pulsed radiofrequency (PRF) at the C2 dorsal root ganglion (DRG), specifically at the C1-2 level, for patients with cervicogenic headaches.

METHODS

The study involved 29 patients with unilateral symptoms from January to July 2023. Headache intensity was measured using the numerical rating scale (NRS), with scores recorded before and after the procedure at specified intervals extending up to 24 weeks. Additionally, the neck disability index (NDI) scores were assessed at baseline, 4, 12 and 24 weeks.

RESULTS

The findings demonstrated significantly reduced headache NRS scores at all post-treatment checkpoints, with notable pain relief rates of 13.79% and 72.41% at 4 weeks, and 17.24% and 68.97% at 12 and 24 weeks, respectively. NDI scores also showed significant reductions at all evaluated post-treatment time points. Importantly, no significant adverse events were observed in any of the individuals.

CONCLUSIONS

Our ultrasound-guided approach could be a safe and effective alternative for managing cervicogenic headaches.

摘要

背景

本研究评估了超声引导下对颈源性头痛患者在C2背根神经节(DRG),特别是在C1-2水平进行脉冲射频(PRF)治疗的有效性和安全性。

方法

该研究纳入了2023年1月至7月的29例单侧症状患者。使用数字评分量表(NRS)测量头痛强度,在治疗前及治疗后直至24周的特定时间间隔记录分数。此外,在基线、4周、12周和24周评估颈部功能障碍指数(NDI)评分。

结果

研究结果表明,在所有治疗后检查点,头痛NRS评分均显著降低,4周时疼痛缓解率分别为13.79%和72.41%,12周和24周时分别为17.24%和68.97%。NDI评分在所有评估的治疗后时间点也显著降低。重要的是,未在任何个体中观察到显著不良事件。

结论

我们的超声引导方法可能是治疗颈源性头痛的一种安全有效的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5f/11934735/7ba22f946c7a/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5f/11934735/d2e5bfb70bda/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5f/11934735/7ba22f946c7a/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5f/11934735/d2e5bfb70bda/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5f/11934735/7ba22f946c7a/fig2.jpg

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Elucidating the Mechanisms of Pulsed Radiofrequency for Pain Treatment.阐明脉冲射频治疗疼痛的机制。
Cureus. 2023 Sep 8;15(9):e44922. doi: 10.7759/cureus.44922. eCollection 2023 Sep.
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Clinical Efficacy Evaluation of Ultrasound-Guided C2 Dorsal Root Nerve Pulsed Radiofrequency Combined with Stellate Ganglion Block in the Treatment of Cervicogenic Headache: A Retrospective Cohort Study.
超声引导下C2背根神经脉冲射频联合星状神经节阻滞治疗颈源性头痛的临床疗效评价:一项回顾性队列研究
J Pain Res. 2023 Jul 28;16:2655-2663. doi: 10.2147/JPR.S409226. eCollection 2023.
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Cervicogenic headache.颈源性头痛。
Musculoskelet Sci Pract. 2023 Aug;66:102787. doi: 10.1016/j.msksp.2023.102787. Epub 2023 Jun 3.
5
Safety and Efficacy of Radiofrequency Ablation and Epidural Steroid Injection for Management of Cervicogenic Headaches and Neck Pain: Meta-Analysis and Literature Review.射频消融和硬膜外类固醇注射治疗颈源性头痛和颈部疼痛的安全性与有效性:荟萃分析与文献综述
Cureus. 2023 Feb 13;15(2):e34932. doi: 10.7759/cureus.34932. eCollection 2023 Feb.
6
In Vivo Ultrasound Imaging of the Spinal Cord and Subarachnoid Space at the C1-C2 Level in Healthy Adult Subjects.健康成人颈 1-颈 2 水平脊髓和蛛网膜下腔的体内超声成像。
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