Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seongnam, Republic of Korea.
Headache. 2020 Nov;60(10):2463-2472. doi: 10.1111/head.13759. Epub 2020 Feb 13.
To evaluate the efficacy and complications of C2 dorsal root ganglion (DRG) pulsed radiofrequency ablation (RFA) for cervicogenic headache (CEH) and to identify factors related to the outcome of the procedure in this retrospective analysis.
Although conventional high-temperature C2 DRG RFA was effective in patients with CEH in previous studies, the effect of pulsed RFA on C2 DRG in cases of CEH has not yet been evaluated.
We examined the electronic medical records of consecutive patients who underwent C2 DRG block for CEH from January 2012 to May 2018 at a pain center. Consequent C2 DRG pulsed RFA was performed for patients in whom the headache recurred after an initial period of relief 24 hours after the C2 DRG block. A successful outcome was defined as at least 50% pain relief at 6 months after C2 DRG pulsed RFA. We also examined variables associated with the outcome and prognostic factors of CEH.
Fluoroscopy-guided C2 DRG block was performed in 114 patients with CEH. Forty-five patients received C2 DRG pulsed RFA and 40.0% among them (18/45, success group) had ≥50% pain relief after 6 months. There were no post-procedure complications throughout the study period. Significantly more patients in the success group than in the failure group had a definite positive response (≥50% pain relief) to a previous C2 DRG block (P < .001).
C2 DRG pulsed RFA may be an effective treatment for patients with CEH, particularly for patients who have previously experienced definite pain reduction after C2 DRG block. However, the limitations of our study design and small number of patients preclude firm conclusions.
评估 C2 背根神经节(DRG)脉冲射频消融(RFA)治疗颈源性头痛(CEH)的疗效和并发症,并在回顾性分析中确定与该手术结果相关的因素。
虽然在以前的研究中,传统的高温 C2 DRG RFA 对 CEH 患者有效,但脉冲 RFA 对 CEH 病例中 C2 DRG 的影响尚未得到评估。
我们检查了 2012 年 1 月至 2018 年 5 月在疼痛中心连续接受 C2 DRG 阻滞治疗 CEH 的患者的电子病历。对于 C2 DRG 阻滞缓解后 24 小时头痛复发的患者,进行后续 C2 DRG 脉冲 RFA。成功的结果定义为 C2 DRG 脉冲 RFA 后 6 个月至少有 50%的疼痛缓解。我们还检查了与结果相关的变量和 CEH 的预后因素。
114 例 CEH 患者行透视引导 C2 DRG 阻滞。45 例患者接受 C2 DRG 脉冲 RFA,其中 40.0%(18/45,成功组)在 6 个月后疼痛缓解≥50%。整个研究期间无术后并发症。与失败组相比,成功组中更多的患者对之前的 C2 DRG 阻滞有明确的阳性反应(≥50%的疼痛缓解)(P<.001)。
C2 DRG 脉冲 RFA 可能是治疗 CEH 患者的有效方法,特别是对之前 C2 DRG 阻滞后疼痛明显减轻的患者。然而,我们的研究设计和患者数量的局限性限制了我们的结论。