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围手术期使用美洛西林与头孢噻肟预防泌尿生殖系统手术后感染

Perioperative mezlocillin vs cefotaxime to prevent infections after genitourinary surgery.

作者信息

Childs S J, Wells W G, Mirelman S

出版信息

Urology. 1985 Jun;25(6):657-61. doi: 10.1016/0090-4295(85)90310-3.

DOI:10.1016/0090-4295(85)90310-3
PMID:4012967
Abstract

This is a report of a randomized, comparative, double-blind study of mezlocillin and cefotaxime given perioperatively to 100 patients undergoing genitourinary surgery. Of 94 evaluable patients, 2 (4.7%) in the mezlocillin group and 2 (3.9%) in the cefotaxime group infections developed in the immediate postoperative period. The difference in these incidences is not statistically significant. One patient with recent bacterial prostatitis and prostatic calculi received cefotaxime and bacteriuria and sepsis developed on the first postoperative day.

摘要

这是一份关于对100例接受泌尿生殖系统手术的患者围手术期给予美洛西林和头孢噻肟的随机、对照、双盲研究报告。在94例可评估患者中,美洛西林组有2例(4.7%)、头孢噻肟组有2例(3.9%)在术后即刻发生感染。这些发生率的差异无统计学意义。1例近期患有细菌性前列腺炎和前列腺结石的患者接受了头孢噻肟治疗,术后第一天出现菌尿和败血症。

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引用本文的文献

1
Cefotaxime. An update of its pharmacology and therapeutic use.头孢噻肟。其药理学与治疗应用的最新进展。
Drugs. 1990 Oct;40(4):608-51. doi: 10.2165/00003495-199040040-00008.