Hussain Nadia, Ibrahim Al Haddad Amal Hussain, Abbass Saima, Alfahl Zina
Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, United Arab Emirates.
AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.
Sleep Med X. 2025 Mar 7;9:100139. doi: 10.1016/j.sleepx.2025.100139. eCollection 2025 Dec.
Sleep quality and its relationship with glycaemic control is of particular interest in the context of geriatric diabetes. We aimed to investigate the potential impact of habitual sleep quality on glycaemic control status among geriatric patients recently diagnosed with type 2 diabetes mellitus (T2DM). A total of 193 geriatric patients recently diagnosed with T2DM in a tertiary-care hospital were selected. A developed questionnaire was used to assess various aspects of sleep quality. Glycaemic control was evaluated through fasting blood glucose levels, HbA1c measurements and number of admissions to the hospital for hypoglycaemic or hyperglycaemic episodes. Patients were divided into Poor Sleep Quality (PSQ, n = 132) and Adequate Sleep Quality (ASQ, n = 61) groups. The PSQ group exhibited significantly worse sleep outcomes, including longer sleep latency (35 ± 9.2 min vs. 15 ± 6.4 min), shorter sleep duration (5 h 42 min vs. 7 h 18 min) and greater use of sleep medications (72 % vs. 22 %). Glycaemic control, measured by HbA1c, was worse in the PSQ group (8.7 ± 1.9 vs. 7.2 ± 1.2; p < 0.01), which also had more frequent severe hypoglycaemic (35 ± 1.4 vs. 8 ± 2.1; p = 0.02) and ketoacidotic episodes (72 ± 1.0 vs. 5 ± 1.1; p = 0.01). These findings suggest an association between poor sleep quality and poorer glycaemic control, with more frequent diabetes-related complications, highlighting the need for further research to explore potential causal relationships and targeted interventions in this population.
在老年糖尿病患者中，睡眠质量及其与血糖控制的关系尤为引人关注。我们旨在研究习惯性睡眠质量对近期诊断为2型糖尿病（T2DM）的老年患者血糖控制状况的潜在影响。选取了一家三级医院中193例近期诊断为T2DM的老年患者。使用一份编制好的问卷来评估睡眠质量的各个方面。通过空腹血糖水平、糖化血红蛋白（HbA1c）测量值以及因低血糖或高血糖发作而住院的次数来评估血糖控制情况。将患者分为睡眠质量差（PSQ，n = 132）组和睡眠质量良好（ASQ，n = 61）组。PSQ组的睡眠结果明显更差，包括更长的入睡潜伏期（35 ± 9.2分钟 vs. 15 ± 6.4分钟）、更短的睡眠时间（5小时42分钟 vs. 7小时18分钟）以及更多地使用助眠药物（72% vs. 22%）。以HbA1c衡量的血糖控制情况在PSQ组更差（8.7 ± 1.9 vs. 7.2 ± 1.2；p < 0.01），该组还出现更频繁的严重低血糖（35 ± 1.4 vs. 8 ± 2.1；p = 0.02）和酮症酸中毒发作（72 ± 1.0 vs. 5 ± 1.1；p = 0.01）。这些发现表明睡眠质量差与血糖控制不佳之间存在关联，且糖尿病相关并发症更频繁，这凸显了进一步研究以探索该人群中潜在因果关系和针对性干预措施的必要性。
