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以三叉神经痛为表现的腮腺腺样囊性癌颅内侵犯:一例报告

Intracranial extension of parotid adenoid cystic carcinoma presenting as trigeminal neuralgia: A case report.

作者信息

Hassouneh Ammar, Sawafta Omar, Jaber Osama, Ali Abd Alkarim, Rahhal Mhd Osama, Sawaftah Zaid, Milhem Fathi, Anabseh Yaqoot

机构信息

Department of Radiology, Hebron Governmental Hospital, Hebron, Palestine.

Department of Medicine, An Najah National University, Nablus, Palestine.

出版信息

Radiol Case Rep. 2025 Mar 8;20(5):2346-2350. doi: 10.1016/j.radcr.2025.02.049. eCollection 2025 May.

DOI:10.1016/j.radcr.2025.02.049
PMID:40129804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11930539/
Abstract

Being rare malignancies, parotid gland adenocarcinomas are most significantly represented by the ACC subtype due to their aggressive nature and propensity for PNI. We present a case of a 56-year-old male with right-sided trigeminal neuralgia and facial palsy, diagnosed with ACC of the parotid gland with intracranial extension. Tumor progression occurred with brain, lung, and liver metastases, so he was placed on palliative care despite chemotherapy. This case underscores the diagnostic and management challenges associated with ACC with PNI.

摘要

腮腺腺癌是罕见的恶性肿瘤,其中腺样囊性癌(ACC)亚型最为常见,因其具有侵袭性和易发生神经周浸润(PNI)的特性。我们报告一例56岁男性患者,患有右侧三叉神经痛和面神经麻痹,诊断为腮腺腺样囊性癌伴颅内侵犯。肿瘤进展出现脑、肺和肝转移,因此尽管进行了化疗,他仍接受了姑息治疗。该病例强调了与伴有神经周浸润的腺样囊性癌相关的诊断和管理挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/e97dc728e68c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/9fe1239fcc8f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/389a4d4c5df7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/a96dc772fb93/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/e97dc728e68c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/9fe1239fcc8f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/389a4d4c5df7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/a96dc772fb93/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c46/11930539/e97dc728e68c/gr4.jpg

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本文引用的文献

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Unraveling the Mysteries of Perineural Invasion in Benign and Malignant Conditions.揭开良性和恶性疾病中神经周围浸润之谜。
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Perineural invasion and perineural spread in periocular squamous cell carcinoma.眼周鳞状细胞癌中的神经周围侵犯和神经周围播散。
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Front Oncol. 2020 Aug 18;10:1493. doi: 10.3389/fonc.2020.01493. eCollection 2020.
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Perineural Invasion in Parotid Gland Malignancies.腮腺恶性肿瘤的神经周围侵犯。
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