Kim Kwangho, Song Juhwan, Chu Hongmin, Kwon Robin, Park Seongjun, Kwon Junhui, Hong Hyeon Joon, Lee Youngyun, Kwon Sanghyuk, Kang Kyungho, Leem Jungtae, Kim Cheol-Hyun
The Academy of Korean Medicine Clinical Anatomy, Seoul, Korea.
Mapo Hongik Korean Medicine Clinic, Seoul, Korea.
J Pain Res. 2025 Mar 19;18:1417-1431. doi: 10.2147/JPR.S509236. eCollection 2025.
Cervical Myofascial Pain Syndrome (CMPS) is a common musculoskeletal disorder that significantly impacts daily life due to pain and restricted movement. This study focuses on Ultrasound-Guided Pharmacopuncture(UGP) to release fascial restrictions and alleviate nerve compression. By utilizing real-time ultrasound imaging, UGP is expected to enhance treatment accuracy, reduce adverse events, and improve clinical outcomes. This study aims to assess the efficacy and safety of UGP compared to Non-Guided Pharmacopuncture (NGP) in patients with acute CMPS.
This multi-center prospective observational comparative study evaluates the efficacy and safety of UGP versus NGP in patients with acute CMPS. A minimum of 100 patients with acute CMPS (≤7 days since symptom onset) will be recruited from two hospitals and five Korean medicine clinics. Participants will be randomly assigned to either the UGP group (receiving ultrasound-guided pharmacopuncture with Hominis Placenta(HP) solution) or the NGP group (receiving non-guided pharmacopuncture with HP solution). A single treatment session will be conducted, with pre- and post-treatment assessments using the Numerical Rating Scale (NRS), Pressure Pain Threshold (PPT), and Range of Motion (ROM). Additionally, a follow-up safety assessment will be conducted via telephone 24-36 hours post-treatment.
This study is the first to evaluate the efficacy and safety of ultrasound-guided HP pharmacopuncture for acute CMPS in a multi-center prospective comparative study. The findings are expected to provide comprehensive evidence supporting ultrasound-guided pharmacopuncture as an effective treatment for myofascial pain and may expand its clinical applications, particularly in Korean medicine clinics.
颈部肌筋膜疼痛综合征（CMPS）是一种常见的肌肉骨骼疾病，因疼痛和活动受限而对日常生活产生重大影响。本研究聚焦于超声引导药物穴位注射（UGP），以松解筋膜限制并减轻神经压迫。通过利用实时超声成像，UGP有望提高治疗准确性、减少不良事件并改善临床结果。本研究旨在评估UGP与非引导药物穴位注射（NGP）相比，在急性CMPS患者中的疗效和安全性。
这项多中心前瞻性观察性比较研究评估了UGP与NGP在急性CMPS患者中的疗效和安全性。将从两家医院和五家韩医诊所招募至少100例急性CMPS患者（症状发作后≤7天）。参与者将被随机分配到UGP组（接受用人胎盘（HP）溶液进行超声引导药物穴位注射）或NGP组（接受用HP溶液进行非引导药物穴位注射）。将进行单次治疗，使用数字评分量表（NRS）、压力疼痛阈值（PPT）和活动范围（ROM）进行治疗前和治疗后评估。此外，将在治疗后24 - 36小时通过电话进行随访安全性评估。
本研究是首次在多中心前瞻性比较研究中评估超声引导HP药物穴位注射治疗急性CMPS的疗效和安全性。研究结果有望提供全面证据，支持超声引导药物穴位注射作为肌筋膜疼痛的有效治疗方法，并可能扩大其临床应用，特别是在韩医诊所。
