Simonsson Otto, Chaturvedi Sankalp, Hendricks Peter S, Stenfors Cecilia U D, Osika Walter, Narayanan Jayanth, Palitsky Roman, Goldberg Simon B
Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; Center for Healthy Minds, University of Wisconsin - Madison, Madison, WI, USA.
Department of Management and Entrepreneurship, Imperial College London, London, UK.
J Psychiatr Res. 2025 Apr;184:457-463. doi: 10.1016/j.jpsychires.2025.03.025. Epub 2025 Mar 17.
Previous research has investigated associations between psychedelic experiences and meditation practice, but knowledge gaps remain. Using a longitudinal research design with a sample of US residents between 18 and 50 years old (N = 13,012), we investigated associations between psychedelic-related and meditation-related variables. The follow-up survey was completed by 7484 respondents, of whom 336 reported psychedelic use during the two-month study. In covariate-adjusted regression models, psychedelic use was associated with greater increases in the number of days of mindfulness and loving-kindness or compassion meditation practice in the past week, especially among those with no prior experience of psychedelics or meditation. Among those who reported psychedelic use, trait mindfulness and trait self-compassion at baseline were associated with less severe challenging psychedelic experiences, as well as lower odds of psychedelic-occasioned thoughts or attempts of self- or other-harm. However, among those who practiced meditation at baseline, psychedelic use was associated with greater increases in past-week frequency of loving-kindness or compassion meditation-related difficulties and impairments. Future research is warranted.
以往的研究调查了迷幻体验与冥想练习之间的关联,但仍存在知识空白。我们采用纵向研究设计,对18至50岁的美国居民样本(N = 13,012)进行研究,调查了与迷幻相关和与冥想相关的变量之间的关联。7484名受访者完成了后续调查,其中336人报告在为期两个月的研究期间使用过迷幻剂。在协变量调整回归模型中,使用迷幻剂与过去一周正念、慈爱或慈悲冥想练习天数的更大增加有关,尤其是在那些没有迷幻剂或冥想经验的人中。在报告使用过迷幻剂的人中,基线时的特质正念和特质自我慈悲与不那么严重的挑战性迷幻体验以及迷幻引发的自我伤害或伤害他人的想法或尝试的较低几率相关。然而,在基线时进行冥想的人中,使用迷幻剂与过去一周慈爱或慈悲冥想相关困难和损害的频率更大增加有关。未来的研究是有必要的。