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2021 - 2022年，法国男性中双重耐药生殖支原体克隆的传播情况

Spread of Dual-Resistant Mycoplasma genitalium Clone among Men, France, 2021-2022.

作者信息

Pereyre Sabine, Laurier-Nadalié C, Balcon Carla, Hénin Nadège, Dolzy Amandine, Gardette Marie, Guiraud Jennifer, Bébéar Cécile

出版信息

Emerg Infect Dis. 2025 Apr;31(4):854-858. doi: 10.3201/eid3104.241602.

DOI:10.3201/eid3104.241602
PMID:40133050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11950270/
Abstract

The 2058T macrolide resistance-associated mutation in 23S rRNA has emerged in Mycoplasma genitalium in France. Using mgpB typing, we documented the spread of a macrolide- and moxifloxacin-resistant ST159 clone, harboring the A2058T and ParC Ser83Ile mutations. In France, that clone is likely circulating among men who have sex with men.

摘要

23S rRNA中与大环内酯类耐药相关的2058T突变已在法国的生殖支原体中出现。通过mgpB分型，我们记录了一个携带A2058T和ParC Ser83Ile突变、对大环内酯类和莫西沙星耐药的ST159克隆的传播情况。在法国，该克隆可能在男男性行为者中传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a138/11950270/532cb6fe5d06/24-1602-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a138/11950270/532cb6fe5d06/24-1602-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a138/11950270/532cb6fe5d06/24-1602-F.jpg

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Estimation of antimicrobial resistance of Belgium, 2022.2022 年比利时抗菌药物耐药性估计。
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gyrA Mutations in Mycoplasma genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-Guided Therapy.
支原体属生殖器gyrA 基因突变及其对莫西沙星耐药失败的影响：是时候进行下一代耐药指导治疗了。
Clin Infect Dis. 2023 Jun 16;76(12):2187-2195. doi: 10.1093/cid/ciad057.
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Prevalence of macrolide and fluoroquinolone resistance-associated mutations in in metropolitan and overseas France.法国大都市和海外地区肺炎支原体对大环内酯类和氟喹诺酮类耐药相关突变的流行情况。
Sex Transm Infect. 2023 Jun;99(4):254-260. doi: 10.1136/sextrans-2022-055466. Epub 2022 Sep 5.
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