Pereyre Sabine, Laurier-Nadalié C, Balcon Carla, Hénin Nadège, Dolzy Amandine, Gardette Marie, Guiraud Jennifer, Bébéar Cécile
Emerg Infect Dis. 2025 Apr;31(4):854-858. doi: 10.3201/eid3104.241602.
The 2058T macrolide resistance-associated mutation in 23S rRNA has emerged in Mycoplasma genitalium in France. Using mgpB typing, we documented the spread of a macrolide- and moxifloxacin-resistant ST159 clone, harboring the A2058T and ParC Ser83Ile mutations. In France, that clone is likely circulating among men who have sex with men.
23S rRNA中与大环内酯类耐药相关的2058T突变已在法国的生殖支原体中出现。通过mgpB分型,我们记录了一个携带A2058T和ParC Ser83Ile突变、对大环内酯类和莫西沙星耐药的ST159克隆的传播情况。在法国,该克隆可能在男男性行为者中传播。