Maki Caroline K, Truong Thao T, Salzer Johanna S, Bestul Nicolette, Cookson Brad T, Kersh Gilbert J, Salipante Stephen J, Lieberman Joshua A, McCormick David W
Emerg Infect Dis. 2025 Apr;31(4):861-863. doi: 10.3201/eid3104.241214.
We identified 34 patients with Coxiella burnetii infection using PCR; 31 (86%) cases were diagnosed from cardiac specimens. Nearly half (15/31, 48%) of those cases were not reported to any channel of national disease surveillance, indicating substantial underreporting for diseases identified using molecular methods at noncommercial laboratories.
我们通过聚合酶链反应(PCR)鉴定出34例感染伯氏考克斯体的患者;其中31例(86%)是从心脏标本中确诊的。这些病例中近一半(15/31,48%)未报告给任何国家疾病监测渠道,这表明在非商业实验室中,使用分子方法鉴定出的疾病存在大量漏报情况。