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对输精管切除术相关长期健康风险的综述。

The review of the long-term health risks associated with vasectomy.

作者信息

Cheng Yu-Sheng, Jiang Tommy, Pourabhari Langroudi Ashkan, Chen Abby L, Basran Satvir S, Eisenberg Michael L

机构信息

Department of Urology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Department of Urology, School of Medicine, Stanford University, Stanford, CA, USA.

出版信息

Int J Impot Res. 2025 Mar 25. doi: 10.1038/s41443-025-01043-4.

DOI:10.1038/s41443-025-01043-4
PMID:40133466
Abstract

Vasectomy, a permanent method of preventing the release of sperm, has been widely used as effective birth control, with millions of men undergoing the procedure worldwide each year. Although vasectomy is effective and relatively simple, it is still a subject that receives considerable scrutiny, especially regarding any health effects. Indeed, the relationship between vasectomy and health risks has been a controversial topic. This review includes the examination of the evidence linking vasectomy to oncologic sequelae (i.e. prostate and testicular cancer). In addition, a review of the literature linking vasectomy to sexual dysfunction, cardiovascular disease, primary progressive aphasia/frontotemporal dementia, anti-sperm antibodies, and reproductive hormone changes is also presented. Overall, vasectomy appears safe with no convincing evidence for long term health risks.

摘要

输精管切除术是一种阻止精子释放的永久性节育方法,已被广泛用作有效的避孕手段,每年全球有数百万男性接受该手术。尽管输精管切除术有效且相对简单,但它仍是一个受到大量审视的主题,尤其是在任何健康影响方面。事实上,输精管切除术与健康风险之间的关系一直是个有争议的话题。本综述包括对将输精管切除术与肿瘤后遗症(即前列腺癌和睾丸癌)联系起来的证据的审查。此外,还对将输精管切除术与性功能障碍、心血管疾病、原发性进行性失语/额颞叶痴呆、抗精子抗体以及生殖激素变化联系起来的文献进行了综述。总体而言,输精管切除术似乎是安全的,没有令人信服的证据表明存在长期健康风险。

相似文献

1
The review of the long-term health risks associated with vasectomy.对输精管切除术相关长期健康风险的综述。
Int J Impot Res. 2025 Mar 25. doi: 10.1038/s41443-025-01043-4.
2
Putative health risks associated with vasectomy.与输精管切除术相关的潜在健康风险。
Urol Clin North Am. 2009 Aug;36(3):337-45. doi: 10.1016/j.ucl.2009.05.004.
3
Vasectomy. What are the long-term risks?输精管切除术。长期风险有哪些?
Med J Aust. 1983 Nov 26;2(11):564-7. doi: 10.5694/j.1326-5377.1983.tb122678.x.
4
Review of Vasectomy Complications and Safety Concerns.输精管切除术并发症及安全问题综述
World J Mens Health. 2021 Jul;39(3):406-418. doi: 10.5534/wjmh.200073. Epub 2020 Jul 30.
5
Is vasectomy harmful to health?输精管切除术对健康有害吗?
Br J Gen Pract. 1997 Jun;47(419):381-6.
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A comprehensive review of the sequelae of male sterilization.男性绝育后遗症的综合综述。
Contraception. 1983 Nov;28(5):455-73. doi: 10.1016/0010-7824(83)90077-x.
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The safety of vasectomy: recent concerns.输精管切除术的安全性:近期关注点
Bull World Health Organ. 1993;71(3-4):413-9.
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Safety and effectiveness of vasectomy.输精管切除术的安全性和有效性。
Fertil Steril. 2000 May;73(5):923-36. doi: 10.1016/s0015-0282(00)00482-9.
9
Status of male contraception.男性避孕的现状。
Obstet Gynecol Annu. 1977;6:355-69.
10
Vasectomy and vasectomy reversal.输精管切除术及输精管复通术。
Curr Ther Endocrinol Metab. 1994;5:333-41.

本文引用的文献

1
Effects of antisperm antibodies post vasectomy reversal on pregnancy rates.输精管复通术后抗精子抗体对妊娠率的影响。
Arch Ital Urol Androl. 2024 May 2;96(2):12335. doi: 10.4081/aiua.2024.12335.
2
Vasectomy and risk of prostate cancer: A Mendelian randomization study and confounder analysis.输精管切除术与前列腺癌风险:孟德尔随机研究和混杂因素分析。
Prostate. 2024 Feb;84(3):269-276. doi: 10.1002/pros.24646. Epub 2023 Oct 31.
3
Down But Not Out: Vasectomy Is Faring Poorly Almost Everywhere-We Can Do Better To Make It A True Method Option.
虽受阻但未被弃:输精管切除术在各地表现不佳——我们可以做得更好,使其成为真正的方法选择。
Glob Health Sci Pract. 2023 Feb 28;11(1). doi: 10.9745/GHSP-D-22-00369.
4
Rising vasectomy volume following reversal of federal protections for abortion rights in the United States.在美国堕胎权联邦保护措施被撤销后,输精管切除术数量不断增加。
Int J Impot Res. 2024 May;36(3):265-268. doi: 10.1038/s41443-023-00672-x. Epub 2023 Feb 14.
5
Vasectomy and Risk of Prostate Cancer: A Systematic Review and Meta-analysis.输精管切除术与前列腺癌风险:一项系统评价和荟萃分析
Eur Urol Open Sci. 2022 May 19;41:35-44. doi: 10.1016/j.euros.2022.04.012. eCollection 2022 Jul.
6
Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis.输精管复通术与体外受精取精术的比较:一项当代的对比分析。
Fertil Steril. 2021 Jun;115(6):1377-1383. doi: 10.1016/j.fertnstert.2021.03.050.
7
Association between vasectomy and risk of prostate cancer: a meta-analysis.输精管切除术与前列腺癌风险之间的关联:一项荟萃分析。
Prostate Cancer Prostatic Dis. 2021 Dec;24(4):962-975. doi: 10.1038/s41391-021-00368-7. Epub 2021 Apr 29.
8
Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline Part I.男性不育的诊断与治疗:AUA/ASRM 指南 第一部分。
J Urol. 2021 Jan;205(1):36-43. doi: 10.1097/JU.0000000000001521. Epub 2020 Dec 9.
9
Impact of Vasectomy on the Development and Progression of Prostate Cancer: Preclinical Evidence.输精管切除术对前列腺癌发生发展的影响:临床前证据
Cancers (Basel). 2020 Aug 15;12(8):2295. doi: 10.3390/cancers12082295.
10
Vasectomy and the risk of prostate cancer in a Finnish nationwide population-based cohort.输精管切除术与前列腺癌风险:一项芬兰全国基于人群的队列研究。
Cancer Epidemiol. 2020 Feb;64:101631. doi: 10.1016/j.canep.2019.101631. Epub 2019 Nov 21.