[糖化血红蛋白、缺氧参数与糖尿病微血管病变之间的关系]
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
作者信息
Gräfenstein K, Duchna W
出版信息
Z Gesamte Inn Med. 1985 Apr 15;40(8):229-31.
In normal persons and in diabetics with and without tissue injuries was tried to find out a connection between the glycolyzed haemoglobin and the parameters of hypoxia. In a small number of cases no clearly evident correlation between the concentrations of the 2,3-diphosphoglycerate and the lactate to the glycohaemoglobins was found. In connection with this investigation pathobiochemical considerations of late diabetic injuries are carried out, which are the consequence of inconveniences in the usability of glucose of diabetics and the connected with this non-enzymatic glycosylation of various proteins.
在正常人和有或无组织损伤的糖尿病患者中，试图找出糖化血红蛋白与缺氧参数之间的联系。在少数病例中，未发现2,3-二磷酸甘油酸和乳酸浓度与糖化血红蛋白之间有明显的相关性。结合这项研究，对晚期糖尿病损伤进行了病理生化方面的思考，这些损伤是糖尿病患者葡萄糖利用不便以及与此相关的各种蛋白质非酶糖基化的结果。
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