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[动脉硬化性循环障碍患者血液中的脂质过氧化物与抗氧化剂]

[Lipid peroxides and antioxidants in the blood of patients with arteriosclerotic circulatory disorders].

作者信息

Peters H J, Voigt H, Köhler H, Vorberg B, Reuter W

出版信息

Z Gesamte Inn Med. 1985 May 1;40(9):276-8.

PMID:4013445
Abstract

Malondialdehyde, vitamin E, glutathione peroxidase and selenium were analysed in the blood of 96 male patients with arteriosclerotic obstructive disease in the region of the leg. Of these 32 patients additionally had manifestations of a coronary or cerebral arteriosclerosis. In the parameters mentioned no significant differences were found between patients with general arteriosclerosis and isolated arteriosclerosis of the leg. Patients with arteriosclerosis and hyperlipoproteinaemia revealed higher values of malondialdehyde than patients without hyperlipoproteinaemia. No correlations were found between malondialdehyde and total cholesterol, triglycerides, vitamin E, glutathione peroxidase as well as selenium.

摘要

对96名患有腿部动脉硬化性阻塞疾病的男性患者的血液进行了丙二醛、维生素E、谷胱甘肽过氧化物酶和硒的分析。其中32名患者还伴有冠状动脉或脑动脉硬化的表现。在所提及的参数方面,全身性动脉硬化患者与单纯腿部动脉硬化患者之间未发现显著差异。患有动脉硬化和高脂蛋白血症的患者丙二醛值高于无高脂蛋白血症的患者。未发现丙二醛与总胆固醇、甘油三酯、维生素E、谷胱甘肽过氧化物酶以及硒之间存在相关性。

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