Wu Yongkang, Zhang Zhi, Qin Wenyi, Chen Weijie, Xu Tuo
Department of Vascular and Thyroid Surgery, the Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Front Oncol. 2025 Mar 11;15:1441726. doi: 10.3389/fonc.2025.1441726. eCollection 2025.
Patient adherence to thyroid-stimulating hormone (TSH) suppression therapy is crucial for optimizing prognosis.
This study aimed to examine the knowledge, attitude, and practice (KAP) toward TSH suppression therapy among patients. This cross-sectional study was conducted at our Hospital between March 2023 and October 2023 and included patients receiving TSH suppression therapy. A self-designed questionnaire was employed to collect their demographic characteristics and KAP. The analysis included 528 valid questionnaires.
The mean knowledge, attitude, and practice scores were 11.66 ± 5.82 (possible range: 0-22), 33.31 ± 4.97 (possible range: 0-40), and 24.46 ± 3.46 (possible range: 0-34), respectively, indicating poor knowledge, favorable attitudes, and moderate practice. The knowledge scores were correlated to the attitude (r=0.399, P<0.001) and practice (r=0.401, P<0.001) scores, while the attitude scores were correlated to the practice scores (r=0.512, P<0.001). The structural equation modeling revealed that knowledge directly influenced attitude (β=0.34, P<0.001) and practice (β=0.13, P<0.001) and indirectly influenced practice through attitude (β=0.10, P<0.001).
Patients receiving TSH suppression therapy in Zhanjiang demonstrated poor knowledge, favorable attitudes, and moderate practices toward TSH suppression therapy.
患者对促甲状腺激素(TSH)抑制治疗的依从性对于优化预后至关重要。
本研究旨在调查患者对TSH抑制治疗的知识、态度和实践(KAP)情况。这项横断面研究于2023年3月至2023年10月在我院进行,纳入接受TSH抑制治疗的患者。采用自行设计的问卷收集其人口统计学特征和KAP情况。分析纳入528份有效问卷。
知识、态度和实践得分的均值分别为11.66±5.82(可能范围:0 - 22)、33.31±4.97(可能范围:0 - 40)和24.46±3.46(可能范围:0 - 34),表明知识水平较差、态度良好、实践情况中等。知识得分与态度得分(r = 0.399,P < 0.001)和实践得分(r = 0.401,P < 0.001)相关,而态度得分与实践得分相关(r = 0.512,P < 0.001)。结构方程模型显示,知识直接影响态度(β = 0.34,P < 0.001)和实践(β = 0.13,P < 0.001),并通过态度间接影响实践(β = 0.10,P < 0.001)。
在湛江接受TSH抑制治疗的患者对TSH抑制治疗的知识水平较差、态度良好、实践情况中等。