Batory I
Z Orthop Ihre Grenzgeb. 1985 Mar-Apr;123(2):201-4. doi: 10.1055/s-2008-1045135.
In this work the author presents his own views regarding the etiology of congenital deformations. The development has been classified according to three phases, taking account of the influence of exogenic and/or endogenous noxae and their secondary effects: 1. The phase between the primordial cell and the second mature cell division; 2. the phase between the second mature cell division and the 12th week of the embryo; 3. the phase following the 12th week of the embryo. During the first phase we are confronted with chromosomal and genetic disturbances. During the second phase, we see disturbances in the process of differentiation and in the third phase anomalies in terms of growth.
在这项工作中,作者提出了他自己关于先天性畸形病因的观点。根据三个阶段对发育进行了分类,同时考虑到外源性和/或内源性有害因素的影响及其继发效应:1. 原始细胞与第二次成熟细胞分裂之间的阶段;2. 第二次成熟细胞分裂与胚胎第12周之间的阶段;3. 胚胎第12周之后的阶段。在第一阶段,我们面临染色体和基因紊乱。在第二阶段,我们看到分化过程中的紊乱,而在第三阶段则是生长方面的异常。