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一名患有脑膜炎球菌性脑膜炎和扩张型心肌病的成年人的脑积水与脑小血管疾病：致命结局

Hydrocephalus and Cerebral Small Vessel Disease in an Adult With Meningococcal Meningitis and Dilated Cardiomyopathy: A Fatal Outcome.

作者信息

Mohamed Yousif, Mohamed Ahmed, Elemam Abubaker, Babiker Abubaker

机构信息

Department of Radiology University of Khartoum Khartoum Sudan.

Department of Internal Medicine University of Khartoum Khartoum Sudan.

出版信息

Clin Case Rep. 2025 Mar 24;13(4):e70343. doi: 10.1002/ccr3.70343. eCollection 2025 Apr.

DOI:10.1002/ccr3.70343
PMID:40134956
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11932878/
Abstract

Meningococcal meningitis can lead to serious neurological complications such as hydrocephalus directly and contribute to cerebral small vessel disease indirectly, especially in patients with pre-existing conditions like dilated cardiomyopathy. Timely identification and aggressive treatment are essential, although the prognosis is often poor when numerous complications are present.

摘要

脑膜炎球菌性脑膜炎可直接导致严重的神经并发症，如脑积水，并间接导致脑小血管疾病，尤其是在患有扩张型心肌病等基础疾病的患者中。及时识别和积极治疗至关重要，尽管存在多种并发症时预后往往很差。

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本文引用的文献

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The meningitis outbreak returns to Niger: Concern, efforts, challenges, and recommendations.脑膜炎疫情在尼日尔卷土重来：关注、努力、挑战和建议。
Immun Inflamm Dis. 2023 Jul;11(7):e953. doi: 10.1002/iid3.953.
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Streptococcus Viridans meningitis in an immunocompetent child: A case report.免疫功能正常儿童的草绿色链球菌脑膜炎：一例报告
Clin Case Rep. 2023 Mar 8;11(3):e7058. doi: 10.1002/ccr3.7058. eCollection 2023 Mar.
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Meningococcal A conjugate vaccine coverage in the meningitis belt of Africa from 2010 to 2021: a modelling study.
2010年至2021年非洲脑膜炎带A群脑膜炎球菌结合疫苗接种率：一项建模研究
EClinicalMedicine. 2023 Jan 5;56:101797. doi: 10.1016/j.eclinm.2022.101797. eCollection 2023 Feb.
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Stroke in Patients with Bacterial Meningitis: A Cohort Study and Meta-Analysis.细菌性脑膜炎患者的脑卒中：一项队列研究和荟萃分析。
Ann Neurol. 2023 Jun;93(6):1094-1105. doi: 10.1002/ana.26618. Epub 2023 Mar 9.
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Cerebral Small Vessel Disease.脑小血管病。
Cell Transplant. 2018 Dec;27(12):1711-1722. doi: 10.1177/0963689718795148. Epub 2018 Sep 25.
6
Vaccine prevention of meningococcal disease in Africa: Major advances, remaining challenges.疫苗预防非洲的脑膜炎球菌病：重大进展，尚存挑战。
Hum Vaccin Immunother. 2018 May 4;14(5):1107-1115. doi: 10.1080/21645515.2017.1412020. Epub 2018 Jan 16.
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Sepsis-Induced Cardiomyopathy: Mechanisms and Treatments.脓毒症诱导的心肌病：机制与治疗
Front Immunol. 2017 Aug 24;8:1021. doi: 10.3389/fimmu.2017.01021. eCollection 2017.
8
Emergence and control of epidemic meningococcal meningitis in sub-Saharan Africa.撒哈拉以南非洲地区流行性脑膜炎球菌性脑膜炎的出现与控制
Pathog Glob Health. 2017 Feb;111(1):1-6. doi: 10.1080/20477724.2016.1274068. Epub 2017 Jan 12.
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Endocarditis in adults with bacterial meningitis.成人细菌性脑膜炎合并心内膜炎。
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Hydrocephalus in adults with community-acquired bacterial meningitis.成人社区获得性细菌性脑膜炎并发脑积水。
Neurology. 2010 Sep 7;75(10):918-23. doi: 10.1212/WNL.0b013e3181f11e10.