Suppr超能文献

老年患者牙龈卟啉单胞菌的检测及其相关的牙周和临床因素

The Detection of Porphyromonas Gingivalis in Geriatrics and Its Associated Periodontal and Clinical Factors.

作者信息

Suhaimi Aina Nabilah, Roop Kishore Yashdev Atri, Shalihin Mohd Shaiful Ehsan, Hamzah Hairul Aini, Abidin Sulhi, Mohammad Aidid Edre, Musa Ramli

机构信息

Department of Health Sciences, International Islamic University Malaysia, Kuantan, MYS.

Department of Kulliyyah Medicine, International Islamic University Malaysia, Kuantan, MYS.

出版信息

Cureus. 2025 Feb 23;17(2):e79522. doi: 10.7759/cureus.79522. eCollection 2025 Feb.

Abstract

BACKGROUND

is one of the important pathogens in the initiation and progression of periodontitis. The findings regarding the bacterium and periodontal status in geriatric subjects are not widely reported. Bacterial analysis is needed to provide more insight regarding the severity of the disease. This study evaluated the presence of in the oral cavity of geriatric patients and found a significant association between infection and medical illness.

METHODS

Periodontal pocket samples were obtained from 32 geriatrics who were chosen randomly from health clinics. Clinical periodontal parameters were recorded during the oral examination. Samples were subjected to DNA extraction and polymerase chain reaction (PCR) amplification. The identification of by PCR assay was determined based on the 16S rRNA subunit amplification. Medical illnesses of patients were recorded. Mild cognitive impairment was diagnosed according to cognitive score assessment and daily function.

RESULTS

Approximately 90.63% (n=29) of geriatric patients had periodontitis. The presence of was significantly associated with periodontal depth and clinical attachment loss (p = 0.037). The extension of periodontal disease, cognitive impairment status, and diabetes status are highly associated with Conclusion: Due to asymptomatic periodontal disease in the early phase, early screening of bacterial detection and oral public health awareness is crucial, especially among elderly groups who are smokers and diabetics. infection is associated with worsening geriatric periodontitis. Adequate oral care and comorbidity control among geriatrics are indeed crucial to preventing disease progression. It is important to improve and modify the local diabetic checklist protocol for geriatric diabetic patients by incorporating oral health and oral microbiome assessments, as well as cognitive assessments.

摘要

背景

是牙周炎发生和发展的重要病原体之一。关于老年受试者中该细菌与牙周状况的研究结果报道并不广泛。需要进行细菌分析以更深入了解疾病的严重程度。本研究评估了老年患者口腔中 的存在情况,并发现 感染与内科疾病之间存在显著关联。

方法

从健康诊所随机选取32名老年人获取牙周袋样本。在口腔检查期间记录临床牙周参数。对样本进行DNA提取和聚合酶链反应(PCR)扩增。基于16S rRNA亚基扩增通过PCR测定法鉴定 。记录患者的内科疾病。根据认知评分评估和日常功能诊断轻度认知障碍。

结果

约90.63%(n = 29)的老年患者患有牙周炎。 的存在与牙周袋深度和临床附着丧失显著相关(p = 0.037)。牙周疾病的扩展、认知障碍状态和糖尿病状态与 高度相关。结论:由于早期牙周疾病无症状,早期进行细菌检测筛查和提高口腔公共卫生意识至关重要,尤其是在老年吸烟者和糖尿病患者群体中。 感染与老年牙周炎病情恶化相关。老年患者进行充分的口腔护理和控制合并症对于预防疾病进展确实至关重要。通过纳入口腔健康和口腔微生物群评估以及认知评估来改进和修改老年糖尿病患者的局部糖尿病检查清单方案很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e66/11936489/04f680dd7824/cureus-0017-00000079522-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验