Gete Dereje G, Dobson Annette J, Montgomery Grant W, Baneshi Mohammad R, Doust Jenny, Mishra Gita D
Australian Women and Girls' Health Research Centre, School of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD, 4006, Australia.
Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.
EClinicalMedicine. 2025 Jan 15;80:103030. doi: 10.1016/j.eclinm.2024.103030. eCollection 2025 Feb.
Women with endometriosis have more hospitalisations compared to those without the condition. However, no longitudinal study has examined hospital admission rates and lengths of stay before and after diagnosis. We examined all-cause hospital admissions and lengths of stay among women with, versus without, endometriosis, and before, versus after, diagnosis.
This study included 13,501 women of reproductive age, born in 1973-78. The Australian Longitudinal Study on Women's Health survey data linked to administrative health records was used to identify women with endometriosis. Hospital admission rates and length of stays were examined using hospital records of patients admitted up to 2022. Analysis was conducted using mixed-effects zero-inflated negative binomial models.
Women with endometriosis were more likely to be admitted to hospitals compared to those without the condition, with an adjusted incidence rate ratio (IRR) of 2.11 (95% CI: 1.83-2.43) for admissions per year. However, they had shorter hospital stays (IRR: 0.90; 0.81-0.99) for days per year and were more often discharged on the same day (odds ratio: 1.27; 1.20-1.33). Post-diagnosis, women experienced more hospitalisations and more days in hospital compared to their pre-diagnosis (IRR: 1.52; 1.22-1.88) and (IRR: 1.81; 1.53-2.14), respectively. Consistent findings were found for women with surgically confirmed or clinically suspected endometriosis.
The higher number of hospitalisations among women with endometriosis, compared to those without, highlights the substantial burden of the condition on healthcare utilisation. The persistent frequent hospitalisations and longer stays post-diagnosis indicate recurrent endometriosis, posing significant management challenges.
The Australian Longitudinal Study on Women's Health is funded by the Australian Government Department of Health and Aged Care. GDM and GWM are Australian National Health and Medical Research Council Leadership Fellows (GNT2009577 and GNT1177194).
与未患子宫内膜异位症的女性相比，患有该疾病的女性住院次数更多。然而，尚无纵向研究考察诊断前后的住院率和住院时长。我们对患有和未患子宫内膜异位症的女性在诊断前后的全因住院情况及住院时长进行了研究。
本研究纳入了1973年至1978年出生的13501名育龄女性。利用与行政健康记录相链接的澳大利亚女性健康纵向研究调查数据来识别患有子宫内膜异位症的女性。通过截至2022年的患者住院记录来考察住院率和住院时长。使用混合效应零膨胀负二项式模型进行分析。
与未患该疾病的女性相比，患有子宫内膜异位症的女性更易住院，每年住院的调整发病率比（IRR）为2.11（95%置信区间：1.83 - 2.43）。然而，她们每年的住院天数较短（IRR：0.90；0.81 - 0.99），且更常在同一天出院（优势比：1.27；1.20 - 1.33）。诊断后，女性的住院次数和住院天数比诊断前更多，分别为（IRR：1.52；1.22 - 1.88）和（IRR：1.81；1.53 - 2.14）。对于经手术确诊或临床疑似患有子宫内膜异位症的女性，也发现了一致的结果。
与未患子宫内膜异位症的女性相比，患有该疾病的女性住院次数更多，这凸显了该疾病对医疗资源利用造成的巨大负担。诊断后持续频繁的住院和更长的住院时长表明子宫内膜异位症复发，带来了重大的管理挑战。
澳大利亚女性健康纵向研究由澳大利亚政府卫生与老年护理部资助。GDM和GWM是澳大利亚国家卫生与医学研究委员会的领导力研究员（GNT2009577和GNT1177194）。
