Muise Eleanor D, Gordon Rachel, Steiding Jacqueline, Sullivan Keri, Sheils Catherine A, Casey Alicia M
New York University Grossman School of Medicine, Division of Pediatric Pulmonary Medicine, Hassenfeld Children's Hospital at NYU Langone Health, New York, New York, USA.
Harvard Medical School, Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Respirology. 2025 Jul;30(7):671-677. doi: 10.1111/resp.70034. Epub 2025 Mar 26.
The vaping epidemic is a public health crisis worldwide. E-cigarette, or vaping product, use-associated lung injury (EVALI) was recognised in the summer of 2019 and resulted in more than 2800 hospitalizations and 60 deaths per the Centres for Disease Control and Prevention (CDC). Vaping refers to the use of E-cigarettes, which are electronic nicotine delivery systems (ENDS) and mimic smoking without combustion. Over 40 million people in the United States vape, of which youth and young adults represent over half. We describe the evaluation and pulmonary complications in a large cohort of adolescents and young adults referred to a Pulmonary Complications of Vaping Clinic.
Youth ages 10-35 with a vaping history and respiratory symptoms underwent a comprehensive diagnostic evaluation. All patients were counselled for vaping cessation. Patients who met criteria for EVALI or probable EVALI with concurrent infection were reported to the Department of Health.
One hundred and thirty patients were referred, and 103 patients underwent comprehensive diagnostic evaluation. Eighty-four percent of patients reported vaping both marijuana and nicotine products. Forty-six percent of patients were diagnosed with EVALI or probable EVALI.
The evolving vaping epidemic demonstrates a need for subject matter expertise in the evaluation and diagnosis of youth with vaping-related lung injury, including EVALI. We report a higher number of youth who met criteria for EVALI with the implementation of a standardised vaping questionnaire and evaluation inclusive of outpatients.
电子烟流行是一场全球范围的公共卫生危机。2019年夏天，人们认识到使用电子烟或雾化产品会导致肺部损伤（EVALI），据美国疾病控制与预防中心（CDC）统计，这已导致超过2800人住院，60人死亡。雾化是指使用电子烟，电子烟属于电子尼古丁传送系统（ENDS），模拟吸烟但无需燃烧。美国有超过4000万人使用电子烟，其中青少年和年轻人占半数以上。我们描述了一大群被转诊至雾化相关肺部疾病诊所的青少年和年轻人的评估情况及肺部并发症。
对10至35岁有雾化史且有呼吸道症状的青少年进行全面的诊断评估。所有患者均接受了关于戒烟的咨询。符合EVALI标准或可能患有EVALI且并发感染的患者被上报给卫生部。
共转诊了130名患者，其中103名患者接受了全面的诊断评估。84%的患者报告同时使用过大麻和尼古丁产品。46%的患者被诊断为EVALI或可能患有EVALI。
不断演变的电子烟流行表明，在评估和诊断与雾化相关的肺部损伤（包括EVALI）的青少年时，需要专业知识。我们报告称，通过实施标准化的雾化问卷和包括门诊患者在内的评估，符合EVALI标准的青少年人数有所增加。
