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新冠疫情对荷兰初级医疗保健中神经性厌食症和神经性贪食症发病率的影响

Impact of the COVID-19 Pandemic on the Incidence of Anorexia and Bulimia Nervosa in Dutch Primary Care.

作者信息

Meier K, van Hoeken D, Kager C C M, van Eeden A E, Oldehinkel A J, Hoek H W

机构信息

Parnassia Psychiatric Institute, The Hague, the Netherlands.

Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

出版信息

Int J Eat Disord. 2025 Jun;58(6):1155-1164. doi: 10.1002/eat.24431. Epub 2025 Mar 26.

Abstract

OBJECTIVE

This study examined the impact of the COVID-19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre-pandemic (2015-2019) and in-pandemic (2020-2022) periods. We hypothesized that the incidence of AN and BN would increase during the pandemic.

METHOD

This retrospective cohort study used data from general practitioners' electronic health records from the Nivel Primary Care Database, representing ~0.8% of the Dutch population. Incident AN and BN cases were identified using DSM-5 criteria. Incidence rates (IR) per 100,000 person-years were calculated and compared using incidence rate ratios (IRRs).

RESULTS

Overall incidence rates of AN and BN did not increase significantly during the pandemic (AN: IRR = 1.2, 95% CI = 0.8-1.8; BN: IRR = 0.9, 95% CI = 0.5-1.8). Non-significant increases in AN were observed among females overall (+29%, IRR = 1.3, 95% CI = 0.9-2.0) and among 10- to 14-year-old females (+28%, IRR = 1.3, 95% CI = 0.4-3.7). The BN incidence decreased significantly among females aged 20-24 years from 53.8 to 10.7 per 100,000 person-years (IRR = 0.2, 95% CI = 0.0-0.9).

DISCUSSION

Contrary to our hypothesis, we did not find increased incidence rates during the pandemic. The overall incidence of AN among females increased non-significantly by 29%. The previously observed rising trend in AN among 10- to 14-year-old females in 1985-2019 did not have a significant sequel into the pandemic era, although it increased by 28%. The BN incidence remained stable overall and decreased significantly among young adult females.

摘要

目的

本研究通过比较疫情前(2015 - 2019年)和疫情期间(2020 - 2022年),考察了新冠疫情对荷兰初级医疗保健中神经性厌食症(AN)和神经性贪食症(BN)发病率的影响。我们假设在疫情期间AN和BN的发病率会上升。

方法

这项回顾性队列研究使用了来自Nivel初级医疗保健数据库中全科医生电子健康记录的数据,该数据库代表了约0.8%的荷兰人口。使用《精神疾病诊断与统计手册》第5版(DSM - 5)标准确定AN和BN的新发病例。计算每10万人年的发病率(IR),并使用发病率比(IRR)进行比较。

结果

在疫情期间,AN和BN的总体发病率没有显著增加(AN:IRR = 1.2,95%置信区间 = 0.8 - 1.8;BN:IRR = 0.9,95%置信区间 = 0.5 - 1.8)。总体女性中AN有不显著的增加(+29%,IRR = 1.3,95%置信区间 = 0.9 - 2.0),在10至14岁女性中也有增加(+28%,IRR = 1.3,95%置信区间 = 0.4 - 3.7)。20至24岁女性中BN的发病率从每10万人年53.8显著降至10.7(IRR = 0.2,95%置信区间 = 0.0 - 0.9)。

讨论

与我们的假设相反,我们没有发现在疫情期间发病率增加。女性中AN的总体发病率不显著地增加了29%。在1985 - 2019年期间,10至14岁女性中之前观察到的AN上升趋势在疫情时代没有显著延续,尽管增加了28%。BN的发病率总体保持稳定,在年轻成年女性中显著下降。

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