Hoek H W, Bartelds A I, Bosveld J J, van der Graaf Y, Limpens V E, Maiwald M, Spaaij C J
Department of Psychiatry, University Hospital Utrecht, The Netherlands.
Am J Psychiatry. 1995 Sep;152(9):1272-8. doi: 10.1176/ajp.152.9.1272.
The purpose of this study was to examine the incidence of anorexia nervosa and bulimia nervosa among patients in primary care and to evaluate the impact of urbanization, age and sex differences, and changes over time.
During 1985-1989, 58 general practitioners, trained in diagnosing eating disorders, registered all of their patients who had diagnoses of anorexia nervosa and/or bulimia nervosa according to strict criteria. The study population (N = 151,781) was 1% of the population of the Netherlands; the distribution of sexes, ages, geographical locations, and degrees of urbanization in the study group was representative of the Dutch population. Main outcome measures were rates of newly detected cases and age-adjusted rate ratios.
The crude annual incidence rate of detected cases in primary care per 100,000 person-years was 8.1 for anorexia nervosa and 11.5 for bulimia nervosa. The incidence of bulimia nervosa was lowest in rural areas, intermediate in urbanized areas, and highest in large cities (6.6, 19.9, and 37.9, respectively, per 100,000 females per year); no rural-urban differences for anorexia nervosa were found. Pronounced sex and age differences in incidence rates were observed. Over the 5-year period, there was no time trend in the incidence of anorexia nervosa, but the incidence of bulimia nervosa tended to increase.
The incidence rates of eating disorders--as defined by detection rates in primary care--are higher than previously reported. Urbanization seems to be a risk factor for bulimia nervosa but not for anorexia nervosa.
本研究旨在调查初级保健患者中神经性厌食症和神经性贪食症的发病率,并评估城市化、年龄和性别差异以及随时间变化的影响。
在1985年至1989年期间,58名接受过饮食失调诊断培训的全科医生,按照严格标准登记了所有被诊断为神经性厌食症和/或神经性贪食症的患者。研究人群(N = 151,781)占荷兰人口的1%;研究组的性别、年龄、地理位置和城市化程度分布代表了荷兰人口。主要结局指标为新发现病例的发生率和年龄调整率比。
初级保健中每10万人年检测到的病例的粗年发病率,神经性厌食症为8.1,神经性贪食症为11.5。神经性贪食症的发病率在农村地区最低,在城市化地区居中,在大城市最高(每年每10万名女性中分别为6.6、19.9和37.9);未发现神经性厌食症存在城乡差异。观察到发病率存在明显的性别和年龄差异。在这5年期间,神经性厌食症的发病率没有时间趋势,但神经性贪食症的发病率有上升趋势。
根据初级保健中的检测率定义的饮食失调发病率高于先前报道。城市化似乎是神经性贪食症的一个危险因素,但不是神经性厌食症的危险因素。