Sairanen H
Acta Pathol Microbiol Immunol Scand A. 1985 May;93(3):109-13. doi: 10.1111/j.1699-0463.1985.tb03928.x.
A new method to determine ventricular volumes of the heart post mortem was developed. Atrioventricular valves are carefully closed with continuous monofilament sutures, and the ventricles are filled with liquid paraffin through the base of the aorta and pulmonary trunk using a standard filling pressure. The effect of various post mortem factors on the volumes of cardiac ventricles was studied using this method. Many factors, such as rigor mortis, time of measurement, mechanical handling of the heart and filling pressure used in the measurement have an effect on the ventricular volume. The volume of ventricles after formalin fixation is only about half of that of fresh hearts handled in the same way. The contraction caused by rigor mortis keeps the volume low and can be relaxed only by manipulation of the heart. The results of measurements are comparable only if the hearts have been manipulated in the same way, have been preserved for the same length of time and under the same conditions, and the volume has been measured using the same filling pressure.
开发了一种用于死后测定心脏心室容积的新方法。使用连续单丝缝线小心关闭房室瓣，然后通过主动脉根部和肺动脉主干，以标准充盈压力向心室中注入液体石蜡。采用该方法研究了各种死后因素对心脏心室容积的影响。许多因素，如尸僵、测量时间、心脏的机械处理以及测量时使用的充盈压力，都会对心室容积产生影响。福尔马林固定后的心室容积仅约为以相同方式处理的新鲜心脏的一半。尸僵引起的收缩使容积降低，只有通过对心脏进行操作才能使其松弛。只有当心脏以相同方式处理、在相同条件下保存相同时间，并且使用相同的充盈压力测量容积时，测量结果才具有可比性。
