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腹腔镜活体供肾肾切除术中与气腹时间延长相关的临床预测因素。

Clinical predictors associated with prolonged pneumoperitoneum time in laparoscopic living donor nephrectomy.

作者信息

Kato Hiroki, Nakane Keita, Okamoto Ayaka, Nishiwaki Teppei, Niwa Kojiro, Tomioka Masayuki, Taniguchi Tomoki, Kawase Makoto, Kawase Kota, Iinuma Koji, Tobisawa Yuki, Koie Takuya

机构信息

Department of Urology, Gifu University Graduate School of Medicine, 1-1 Yanagito, Gifu, 501-1194, Japan.

出版信息

Clin Exp Nephrol. 2025 Mar 26. doi: 10.1007/s10157-025-02663-2.

Abstract

BACKGROUND

Kidney transplantation (KT) is a useful treatment option for patients with end-stage chronic kidney disease to avoid dialysis and achieve a good quality of life. In Japan, approximately 90% of kidneys for KT are obtained from living kidney donors. Laparoscopic renal nephrectomy (LDN) is the most commonly performed KT procedure in Japan. We aimed to determine the clinical variables that influence the prolongation of pneumoperitoneum time (PT) in LDN.

METHOD

This retrospective study was carried out on 218 consecutive patients who underwent LDN at Gifu University Hospital. T The enrolled patients were divided into two groups according to the third quartile of PT in the LDN, with those in the lower third quartile (Q3) as Group 1 and those in the upper Q3 as Group 2. The primary endpoint was identification of predictive factors for prolonged PT.

RESULT

In total, 178 patients were included in the analysis. For all patients, the median PT, estimated blood loss, and warm ischemic time were 170 min, 20 mL, and 4 min, respectively. Significantly longer PT was observed in Group 2 than in Group 1. Multiple regression analysis results showed that male donors, body mass index ≥ 25 kg/m, and donors with more than two renal arteries were independent predictive factors for PT prolongation.

CONCLUSION

Male sex, BMI ≥ 25 kg/m, and two or more renal arteries are predictive factors for prolonged PT for donors in LDN.

摘要

背景

肾移植(KT)是终末期慢性肾病患者避免透析并获得良好生活质量的有效治疗选择。在日本,约90%的肾移植供肾来自活体供肾者。腹腔镜肾切除术(LDN)是日本最常用的肾移植手术方式。我们旨在确定影响LDN中气腹时间(PT)延长的临床变量。

方法

本回顾性研究对岐阜大学医院连续218例行LDN的患者进行。根据LDN中PT的第三个四分位数将纳入患者分为两组,PT处于较低第三个四分位数(Q3)的患者为第1组,PT处于较高Q3的患者为第2组。主要终点是确定PT延长的预测因素。

结果

总共178例患者纳入分析。所有患者的中位PT、估计失血量和热缺血时间分别为170分钟、20毫升和4分钟。第2组的PT明显长于第1组。多元回归分析结果显示,男性供者、体重指数≥25kg/m²以及有两条以上肾动脉的供者是PT延长的独立预测因素。

结论

男性、BMI≥25kg/m²以及两条或更多肾动脉是LDN供者PT延长的预测因素。

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