Department of Surgery, Division of HPB & Transplant Surgery, University Medical Centre Rotterdam, Dr. Molewaterplein 40, Erasmus MC, 3015 GD, Rotterdam, The Netherlands.
Department of Gastroenterological Surgery, Dentistry, and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.
Surg Endosc. 2021 Jun;35(6):2889-2895. doi: 10.1007/s00464-020-07727-w. Epub 2020 Jun 15.
Several difficulty grading systems have been developed as a useful tool for selecting patients and training surgeons in laparoscopic procedures. However, there is little information on predicting the difficulty of laparoscopic donor nephrectomy (LDN). The aim of this study was to develop a grading system to predict the difficulty of LDN.
Data of 1741 living donors, who underwent pure or hand-assisted LDN between 1994 and 2018 were analyzed. Multivariable analyses were performed to identify factors associated with prolonged operative time, defined as a difficulty index with 0 to 8. The difficulty of LDN was classified into three levels based on the difficulty index.
Multivariable analyses identified that male (odds ratio [OR] 1.69, 95% CI 1.37-2.09, P < 0.001), BMI > 28 (OR 1.36, 95% CI 1.08-1.72, P = 0.009), pure LDN (OR 1.99, 95% CI 1.53-2.60, P < 0.001), multiple renal arteries (OR 2.38, 95% CI 1.83-3.10, P < 0.001) and multiple renal veins (OR 2.18, 95% CI 1.52-3.16, P < 0.001) were independent risk factors influencing prolonged operative time. The difficulty index based on these factors was calculated and categorized into three levels: low (0-2), intermediate (3-5), and high (6-8) difficulty. Operative time was significantly longer in the high difficulty group (225 min) than in the low (169 min, P < 0.001) and intermediate difficulty group (194 min, P < 0.001). The conversion rate was higher in the high difficulty group (4.4%) than in the low (2.1%, P = 0.04) and the intermediate difficulty group (3.0%, P = 0.27). No significant difference in major complications was found between the groups.
We developed a novel grading system with simple preoperative donor factors to predict the difficulty of LDN. This grading system may help surgeons in patient selection to advance their experiences and/or teach fellows from simple to difficult LDN.
已经开发出几种困难分级系统,作为选择患者和培训腹腔镜手术医生的有用工具。然而,关于预测腹腔镜供肾切除术(LDN)难度的信息很少。本研究的目的是建立一种分级系统来预测 LDN 的难度。
分析了 1994 年至 2018 年间接受纯腹腔镜或手助腹腔镜供肾切除术的 1741 名活体供者的数据。多变量分析用于确定与手术时间延长相关的因素,定义为难度指数为 0 至 8。根据难度指数将 LDN 的难度分为三个级别。
多变量分析确定男性(比值比 [OR] 1.69,95%置信区间 [CI] 1.37-2.09,P<0.001)、BMI>28(OR 1.36,95%CI 1.08-1.72,P=0.009)、纯腹腔镜供肾切除术(OR 1.99,95%CI 1.53-2.60,P<0.001)、多发性肾动脉(OR 2.38,95%CI 1.83-3.10,P<0.001)和多发性肾静脉(OR 2.18,95%CI 1.52-3.16,P<0.001)是影响手术时间延长的独立危险因素。基于这些因素的难度指数进行了计算并分为三个级别:低(0-2)、中(3-5)和高(6-8)难度。高难度组的手术时间明显长于低难度组(225 分钟)和中难度组(194 分钟,P<0.001)。高难度组的转化率(4.4%)高于低难度组(2.1%,P=0.04)和中难度组(3.0%,P=0.27)。各组之间主要并发症无显著差异。
我们开发了一种新的分级系统,使用简单的术前供者因素来预测 LDN 的难度。该分级系统可能有助于外科医生选择患者,提高他们的经验,或从简单到困难的 LDN 教学员。