He Junhui, Li Shuhui, Li Lihua, Gao Yulan, Sun Yunji, Cheng Lin
Department of Urology, Heze Municipal Hospital, Heze 274000, China.
Department of Urology, Shandong Provincial Third Hospital, Shandong University, Jinan 250012, China.
Int J Surg Case Rep. 2025 Apr;129:111195. doi: 10.1016/j.ijscr.2025.111195. Epub 2025 Mar 24.
Retroperitoneal schwannoma is usually asymptomatic, and is often found incidentally during physical examination. It is easy to be misdiagnosed as paraganglioma, retroperitoneal malignant tumor and giant lymphocyte hyperplasia. Accurate preoperative diagnosis is helpful for clinicians to make surgical plans and preoperative preparations. This paper reports a case of retroperitoneal schwannoma. Preoperative imaging suggested a neurogenic tumor behind the left renal artery. The treatment was laparoscopic retroperitoneal tumor resection. The postoperative pathological diagnosis was retroperitoneal schwannoma.
The 52-year-old female patient was admitted to the hospital due to a left retroperitoneal tumor. Preoperative CT and MRI showed neurogenic tumor. After patient authorization, left retroperitoneal tumor resection was performed under laparoscopy. The postoperative pathological diagnosis was retroperitoneal schwannoma. The patient was followed up for 1 year without recurrence or metastasis.
The CT features of retroperitoneal schwannoma may be lower than that of the muscle tissue at the same level, with uneven density, cystic lesions, hemorrhage, calcification and other characteristics. Enhanced CT can show progressive enhancement, mild to moderate enhancement in the arterial phase and moderate enhancement in the delayed phase. MRI showed slightly high signal intensity in the center of T2WI lesions, obvious high signal intensity at the edge, and high signal intensity on DWI. The diagnosis of retroperitoneal schwannoma depends on postoperative pathological examination. S-100 protein is one of its specific markers, and most of them are positive. Retroperitoneal schwannoma is mostly benign, but there are also some patients with malignant tumors. The first choice of treatment is complete resection of the tumor, and the tumor margin can also be negative by removing part of the normal adjacent tissue. The survival rate of patients with complete resection can reach 100 %, and the recurrence rate of patients with incomplete resection is about 5-10 %.
Retroperitoneal schwannoma is a relatively rare retroperitoneal tumor. Enhanced CT can show progressive enhancement, mild to moderate enhancement in the arterial phase and moderate enhancement in the delayed phase. MRI showed slightly high signal intensity in the center of T2WI lesions, obvious high signal intensity at the edge, and high signal intensity on DWI. The diagnosis of retroperitoneal schwannoma depends on postoperative pathological examination, and S-100 protein is one of its specific markers. Retroperitoneal schwannoma is mostly benign, but there are also some malignant tumors. The treatment of retroperitoneal schwannoma is the first choice to completely remove the tumor.
腹膜后神经鞘瘤通常无症状,常在体检时偶然发现。它容易被误诊为副神经节瘤、腹膜后恶性肿瘤和巨大淋巴细胞增生症。准确的术前诊断有助于临床医生制定手术方案和进行术前准备。本文报道一例腹膜后神经鞘瘤病例。术前影像学检查提示左肾动脉后方有一神经源性肿瘤。治疗方法为腹腔镜腹膜后肿瘤切除术。术后病理诊断为腹膜后神经鞘瘤。
该52岁女性患者因左腹膜后肿瘤入院。术前CT和MRI显示为神经源性肿瘤。经患者授权后,在腹腔镜下行左腹膜后肿瘤切除术。术后病理诊断为腹膜后神经鞘瘤。患者随访1年,无复发或转移。
腹膜后神经鞘瘤的CT表现可能低于同一层面的肌肉组织,密度不均匀,有囊性病变、出血、钙化等特征。增强CT可显示渐进性强化,动脉期轻度至中度强化,延迟期中度强化。MRI显示T2WI序列病变中心呈稍高信号,边缘呈明显高信号,DWI序列呈高信号。腹膜后神经鞘瘤的诊断依赖于术后病理检查。S-100蛋白是其特异性标志物之一,大多数呈阳性。腹膜后神经鞘瘤大多为良性,但也有一些为恶性肿瘤。治疗首选完整切除肿瘤,切除部分正常相邻组织时肿瘤边缘也可为阴性。完整切除患者的生存率可达100%,不完全切除患者的复发率约为5%-10%。
腹膜后神经鞘瘤是一种相对少见的腹膜后肿瘤。增强CT可显示渐进性强化,动脉期轻度至中度强化,延迟期中度强化。MRI显示T2WI序列病变中心呈稍高信号,边缘呈明显高信号,DWI序列呈高信号。腹膜后神经鞘瘤的诊断依赖于术后病理检查,S-100蛋白是其特异性标志物之一。腹膜后神经鞘瘤大多为良性,但也有一些恶性肿瘤。腹膜后神经鞘瘤的治疗首选完整切除肿瘤。