Choate Radmila, Conwell Darwin L, Hill Rachel L, Adams Alyce Sophia, Yadav Dhiraj, Yazici Cemal
Department of Epidemiology and Environmental Health, College of Public Health, University of Kentucky, 111 Washington Ave, Suite 215, Lexington, KY, 40536, USA.
Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
J Racial Ethn Health Disparities. 2025 Mar 26. doi: 10.1007/s40615-025-02402-z.
Pancreatic diseases, such as acute pancreatitis (AP), chronic pancreatitis (CP), and pancreatic ductal adenocarcinoma (PDAC), disproportionately affect Black/African American (AA) communities in the United States, leading to high incidence, prevalence, and mortality rates. This paper outlines disparities in pancreatic diseases among AAs and explores contributing factors beyond individual biology and behavior, emphasizing the role of social determinants of health (SDoH), including poor access to healthcare, lack of inclusion in research studies, and other crucial systemic and structural factors in historically marginalized AA communities. This review identifies barriers to pancreatic disease research in AAs and advocates for addressing healthcare disparities through community engagement, healthcare workforce diversity, partnerships with minority-serving healthcare facilities, and community-led initiatives targeting lifestyle modification. In conclusion, reducing pancreatic disease disparities in AA communities requires acknowledging systemic influences, engaging frontline communities, implementing innovative healthcare delivery models, addressing modifiable risk factors and structural inequities, and promoting inclusivity in research and healthcare.
胰腺疾病，如急性胰腺炎（AP）、慢性胰腺炎（CP）和胰腺导管腺癌（PDAC），对美国黑人/非裔美国人（AA）群体的影响尤为严重，导致发病率、患病率和死亡率居高不下。本文概述了AA人群中胰腺疾病的差异，并探讨了个体生物学和行为之外的影响因素，强调了健康的社会决定因素（SDoH）的作用，包括获得医疗保健的机会有限、未被纳入研究、以及历史上被边缘化的AA社区中其他关键的系统和结构因素。本综述确定了AA人群胰腺疾病研究的障碍，并倡导通过社区参与、医疗保健劳动力多元化、与服务少数群体的医疗机构建立伙伴关系，以及针对生活方式改变的社区主导倡议来解决医疗保健差异问题。总之，减少AA社区的胰腺疾病差异需要认识到系统影响，让一线社区参与进来，实施创新的医疗服务模式，解决可改变的风险因素和结构不平等问题，并促进研究和医疗保健中的包容性。
