From the Division of Gastroenterology and Hepatology, University of Illinois at Chicago, Chicago, IL.
Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA.
Pancreas. 2022 Jul 1;51(6):598-603. doi: 10.1097/MPA.0000000000002072.
Recruitment and retention of patients with acute pancreatitis (AP) in clinical studies can be challenging. While some obstacles are similar to other clinical conditions, some are unique to AP. Identifying potential barriers early and developing targeted solutions can help optimize recruitment and retention in AP studies. Such pre-emptive and detailed planning can help prospective, longitudinal studies focus on exocrine and endocrine complications of AP in accurately measuring outcomes. This article highlights the challenges in recruitment and retention strategies in AP studies and reviews available resources to create opportunities to address them. We describe the multifaceted approach used by the Recruitment and Retention Committee of the Type 1 Diabetes in Acute Pancreatitis Consortium, which builds upon earlier experiences to develop a recruitment and retention plan for the DREAM (Diabetes RElated to Acute pancreatitis and its Mechanisms) study.
招募和保留急性胰腺炎（AP）患者参与临床研究可能具有挑战性。虽然一些障碍与其他临床情况相似，但也有一些是 AP 特有的。及早发现潜在障碍并制定有针对性的解决方案有助于优化 AP 研究的招募和保留。这种先发制人和详细的计划可以帮助前瞻性、纵向研究专注于 AP 的外分泌和内分泌并发症，从而准确衡量结果。本文强调了 AP 研究中招募和保留策略面临的挑战，并回顾了可用资源，以创造机会来解决这些问题。我们描述了 1 型糖尿病急性胰腺炎联盟的招募和保留委员会所采用的多方面方法，该方法基于早期经验，为 DREAM（糖尿病与急性胰腺炎及其机制）研究制定了招募和保留计划。
