Jiang Daiji, Liu Xiaowei, Lin Qian, Wang Guyi, Wang Gang, Zhang Dandan
Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Department of Traditional Chinese Medicine, Shanxi Provincial People's Hospital, No. 256 Friendship West Road, Xi'an, Shaanxi Province, China.
Sci Rep. 2025 Mar 26;15(1):10388. doi: 10.1038/s41598-025-93795-8.
This systematic review and meta-analysis aim to summarize and analyze current research on the effects of MI on neurodevelopment in children of all ages and health statuses to provide a reference for music therapy (MT) and its clinical research in pediatrics. We conducted a comprehensive search of PubMed, Embase, Web of Science, and Cochrane Library databases up to December 2023, focusing on randomized controlled trials that evaluated neurodevelopmental outcomes following MI. Our analysis, which included seven studies involving 337 participants, employed standardized mean difference (SMD) calculations to assess outcomes across multiple neurodevelopmental scales. While no significant cognitive improvements were observed on the Bayley-III scale, positive effects were noted in language, motor skills, and IQ scores when assessed via Gesell, CSBQ, and IQ scales. Our research underscores the potential of music intervention in the process of children's neurodevelopment, including cognitive function, language, motor and IQ. Based on the limitations, researchers should carefully design their MI protocols, ensuring standardization and avoiding probable confounding factors such as regional specificity, age ranges and special populations, it will contribute to more robust results and improve the comparability of findings across studies.
本系统评价和荟萃分析旨在总结和分析当前关于音乐干预对各年龄段和健康状况儿童神经发育影响的研究，为音乐治疗及其儿科临床研究提供参考。我们全面检索了截至2023年12月的PubMed、Embase、Web of Science和Cochrane图书馆数据库，重点关注评估音乐干预后神经发育结局的随机对照试验。我们的分析纳入了7项研究，共337名参与者，采用标准化均数差（SMD）计算来评估多个神经发育量表的结局。虽然在贝利婴幼儿发展量表第三版上未观察到显著的认知改善，但通过盖塞尔发育量表、儿童行为问卷（CSBQ）和智商量表评估时，在语言、运动技能和智商得分方面发现了积极影响。我们的研究强调了音乐干预在儿童神经发育过程中的潜力，包括认知功能、语言、运动和智商。基于这些局限性，研究人员应仔细设计他们的音乐干预方案，确保标准化并避免可能的混杂因素，如地区特异性、年龄范围和特殊人群，这将有助于获得更可靠的结果并提高研究结果之间的可比性。
