Ohnishi K, Nakayama T, Koen H, Saito M, Saito M, Chin N, Terabayashi H, Iida S, Nomura F, Okuda K
Am J Gastroenterol. 1985 Jul;80(7):561-4.
The interrelationship between the type and degree of spontaneous portal systemic shunting, and portal vein pressure was studied in 155 patients with liver disease by catheterizing the portal vein. The degree of portal vein shunting was measured in 100 patients and that of splenic vein shunting in 50 and that of total portal systemic shunting in 52, using macroaggregated radioalbumin. Increasing portal vein pressures were associated with progressively higher indices of portal vein shunt, splenic vein shunt, and total portal systemic shunt up to a certain level. Beyond this level, portal vein pressure did not increase further, and rather it decreased with further increasing degrees of splenic vein shunt and total portal systemic shunt. These results indicate that spontaneous portal systemic shunt keeps the portal vein pressure within certain limits or decreases it.
通过门静脉插管，对155例肝病患者的自发性门体分流类型和程度与门静脉压力之间的相互关系进行了研究。采用大颗粒放射性白蛋白，对100例患者测量了门静脉分流程度，对50例患者测量了脾静脉分流程度，对52例患者测量了总的门体分流程度。门静脉压力升高与门静脉分流、脾静脉分流及总的门体分流指数逐渐升高相关，直至达到某一水平。超过这一水平后，门静脉压力不再进一步升高，相反，随着脾静脉分流和总的门体分流程度进一步增加，门静脉压力反而降低。这些结果表明，自发性门体分流可使门静脉压力维持在一定范围内或使其降低。
