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维生素D缺乏情况下颌面部区域的放射诊断与骨骼骨密度:一项初步研究。

Radiation Diagnostics of the Maxillofacial Region and Skeleton Bone Density in the Case of Vitamin D Insufficiency: A Pilot Study.

作者信息

Diachkova Ekaterina, Tarasenko Svetlana, Skachkova Marina, Zhilkov Yury, Serova Natalia, Babkova Anna, Volel Beatrice, Blinova Ekaterina, Kytko Elizaveta, Meylanova Renata, Zaborova Victoria, Kytko Olesya

机构信息

Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia.

Department of Operative Surgery and Topographic Anatomy, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.

出版信息

Life (Basel). 2025 Mar 17;15(3):480. doi: 10.3390/life15030480.

DOI:10.3390/life15030480
PMID:40141824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11944190/
Abstract

(1) Background: A decrease in bone mineral density has been noted not only in at-risk patients (e.g., postmenopausal women) but also in young and middle-aged individuals due to changes in lifestyle. The aim of the study was to find a possible correlation for dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) with cone beam computed tomography (CBCT) of the jaws. (2) Methods: A total of 24 patients (14 women and 10 men aged 25 to 50 years) with partial secondary tooth loss and vitamin D insufficiency underwent cone beam computed tomography of the jaws and skeletal mineral density assessment using DXA ( = 12) and QCT ( = 12). (3) Results: When conducting CBCT of the jaws, a predominance of bone tissue type D3 (350-850 Hu) on the upper jaw ( > 0.05 (F = 0.68) and D2 (850-1350 Hu) on the lower jaw ( > 0.05 (F = 1) was revealed. According to the results of QCT densitometry of the skeleton, signs of osteopenia were found in four patients (with vitamin D3 deficiency) (33%) according to DXA; signs of osteopenia were found in six patients (with severe deficiency and deficiency of vitamin D3) (50%). The difference between QCT and DXA was not significant ( > 0.05) for each group. The significant strong correlation between CBCT and DXA or QCT was not found ( > 0.05). (4) Conclusions: Primary changes in bone density can be detected earlier in the dental system using cone beam computed tomography of the jaws. At the same time, the question of using a specific densitometry method-DXA or QCT-remains open, as their results correlating with CBCT optical density was not approved.

摘要

(1) 背景:不仅在高危患者(如绝经后女性)中,而且在年轻和中年个体中,由于生活方式的改变,骨矿物质密度都出现了下降。本研究的目的是寻找双能X线吸收法(DXA)和定量计算机断层扫描(QCT)与颌骨锥形束计算机断层扫描(CBCT)之间可能存在的相关性。(2) 方法:共有24例部分牙齿继发性缺失且维生素D不足的患者(14名女性和10名男性,年龄在25至50岁之间)接受了颌骨锥形束计算机断层扫描,并使用DXA(n = 12)和QCT(n = 12)进行骨骼矿物质密度评估。(3) 结果:在进行颌骨CBCT检查时,上颌骨主要为D3型骨组织(350 - 850 Hu)(P > 0.05(F = 0.68)),下颌骨主要为D2型骨组织(850 - 1350 Hu)(P > 0.05(F = 1))。根据骨骼QCT骨密度测量结果,DXA显示4例患者(维生素D3缺乏)(33%)有骨质减少迹象;QCT显示6例患者(维生素D3严重缺乏和缺乏)(50%)有骨质减少迹象。每组中QCT和DXA之间的差异不显著(P > 0.05)。未发现CBCT与DXA或QCT之间存在显著的强相关性(P > 0.05)。(4) 结论:使用颌骨锥形束计算机断层扫描可以在牙齿系统中更早地检测到骨密度的原发性变化。同时,关于使用特定的骨密度测量方法——DXA或QCT——的问题仍然悬而未决,因为它们与CBCT光学密度相关的结果尚未得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/dbb61276e523/life-15-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/8090f3b22cf6/life-15-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/dbf5ba1a01f3/life-15-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/dbb61276e523/life-15-00480-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/8090f3b22cf6/life-15-00480-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/dbf5ba1a01f3/life-15-00480-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8425/11944190/dbb61276e523/life-15-00480-g003.jpg

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本文引用的文献

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High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis.南亚成年人维生素 D 缺乏症的高发率:系统评价和荟萃分析。
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