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挪威奥斯陆国家医院员工中乙肝表面抗原抗体:一项患病率研究。

Antibody to hepatitis B surface antigen among employees in the National Hospital, Oslo, Norway: a prevalence study.

作者信息

Hovig B, Rollag H, Dahl O

出版信息

Am J Epidemiol. 1985 Jul;122(1):127-34. doi: 10.1093/oxfordjournals.aje.a114071.

Abstract

During the last decade, several studies of serologic markers of hepatitis B virus infections in hospital personnel have demonstrated an increased prevalence of antibodies to hepatitis B virus (anti-HB) compared with the general population. Norway has a very low incidence rate of hepatitis B as seen on a global scale, and this study was performed to evaluate the infection risk by hospital workers in such environments. The employees, 2,546 (94.7% of the population), in the 800-bed National Hospital in Oslo were tested for antibody to hepatitis B surface antigen (anti-HBs) in serum. Five per cent (128 persons) were anti-HBs-positive; this was only slightly higher than that in the general Norwegian population. Male employees were more often positive than females (7.0% vs. 4.4%). Staff more than 50 years of age or with 16 or more years of employment in the health services had a rate twice as high as the rest of the employees. Staff in the porter services (mostly men) had a higher rate than others, whereas the rates in the different professional groups showed no statistical differences. Contrary to many other studies, significant differences in prevalence according to frequency of patient contact or blood handling were not found.

摘要

在过去十年中,针对医院工作人员乙肝病毒感染血清学标志物的多项研究表明,与普通人群相比,乙肝病毒抗体(抗-HB)的患病率有所上升。从全球范围来看,挪威的乙肝发病率很低,开展这项研究是为了评估医院工作人员在这样的环境中的感染风险。对奥斯陆拥有800张床位的国家医院的2546名员工(占总人数的94.7%)进行了血清乙肝表面抗原抗体(抗-HBs)检测。5%(128人)的员工抗-HBs呈阳性;这仅略高于挪威普通人群。男性员工的阳性率高于女性(7.0%对4.4%)。年龄超过50岁或在医疗卫生服务领域工作16年及以上的员工,其阳性率是其他员工的两倍。搬运服务部门的员工(大多为男性)阳性率高于其他部门,而不同专业组的阳性率没有统计学差异。与许多其他研究相反,未发现根据接触患者频率或处理血液频率在患病率上存在显著差异。

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