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成人与儿童住院患者及门诊患者细菌性结膜炎的比较分析

Comparative Analysis of Bacterial Conjunctivitis in the Adult and Pediatric Inpatient vs. Outpatient Population.

作者信息

Voinescu Adela, Musuroi Corina, Licker Monica, Muntean Delia, Musuroi Silvia-Ioana, Baditoiu Luminita Mirela, Dugaesescu Dorina, Jumanca Romanita, Munteanu Mihnea, Cosnita Andrei

机构信息

Doctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Department of Microbiology, Multidisciplinary Research Center of Antimicrobial Resistance, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

出版信息

Microorganisms. 2025 Feb 20;13(3):473. doi: 10.3390/microorganisms13030473.

Abstract

The etiology and resistance pattern of bacterial conjunctivitis varies depending on the patient's care setting and age. A retrospective, observational study was conducted in a tertiary care teaching hospital. A total of 126 patients-76 adults and 50 children-diagnosed with conjunctival infection during inpatient or ambulatory care were analyzed. In the samples of adult patients, isolates were represented by Gram-positive cocci (57.7%; spp., ) followed by (17.97%; , , spp.), and non-fermenters (7.69%; spp., ). Multidrug-resistant (52.17%) and extensively drug-resistant (21.73%) pathogens (predominantly Gram-negative bacilli) were identified in conjunctival swabs of hospitalized adult patients. The main isolates (55.77%) identified in children's conjunctival swabs belonged to , , and , followed by (19.22%; , , and fungi (3.48%). Methicillin-resistant (35.71%) and extended-spectrum beta-lactamase-producing (8.7%) were identified in the pediatric subgroup of patients. In critically ill adult patients assisted in the intensive care or burn functional units, bacterial conjunctivitis followed the pattern of infections and antimicrobial resistance specific to these categories of patients. In the case of hospitalized children, conjunctivitis was an integral part of the age-related pathology.

摘要

细菌性结膜炎的病因及耐药模式因患者的护理环境和年龄而异。在一家三级护理教学医院进行了一项回顾性观察研究。共分析了126例在住院或门诊护理期间被诊断为结膜感染的患者,其中76例为成人,50例为儿童。在成年患者样本中,分离菌以革兰氏阳性球菌为主(57.7%; 菌属, ),其次是 菌(17.97%; 菌属、 菌属、 菌属)和非发酵菌(7.69%; 菌属)。在住院成年患者的结膜拭子中鉴定出多药耐药(52.17%)和广泛耐药(21.73%)病原体(主要是革兰氏阴性杆菌)。在儿童结膜拭子中鉴定出的主要分离菌(55.77%)属于 菌属、 菌属和 菌属,其次是 菌(19.22%; 菌属、 菌属、 菌属)和真菌(3.48%)。在儿童患者亚组中鉴定出耐甲氧西林 菌(35.71%)和产超广谱β-内酰胺酶 菌(8.7%)。在重症监护室或烧伤功能单元接受治疗的重症成年患者中,细菌性结膜炎遵循这些类型患者特有的感染模式和抗菌药物耐药模式。对于住院儿童,结膜炎是与年龄相关病理的一个组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca2/11944974/b2a5962e04c0/microorganisms-13-00473-g001.jpg

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