Salles Gleidson Biasi Carvalho, Pilati Giulia Von Tönnemann, Savi Beatriz Pereira, Dahmer Mariane, Muniz Eduardo Correa, Vogt Josias Rodrigo, Lima Neto Antonio José de, Fongaro Gislaine
Laboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Zoetis Industry of Veterinary Products LTDA, São Paulo 04709-111, SP, Brazil.
Microorganisms. 2025 Feb 27;13(3):521. doi: 10.3390/microorganisms13030521.
Infectious bronchitis virus (IBV) poses a significant threat to poultry worldwide, necessitating robust surveillance and vaccination strategies. This study aimed to conduct IBV surveillance in Brazil, assess potential vaccine viral escapes, and evaluate vaccine persistence in vaccinated broilers. A total of 1000 tracheal swabs from 100 flocks across six states were analyzed using RT-PCR. The results showed that 91% of the flocks tested positive for IBV. The detected strains included GI-1, GI-11, and GI-23. Notably, 90% of batches received vaccines containing either GI-1 or GI-11 lineages. The study revealed vaccine persistence in 67 samples between days 16 and 32 post-vaccination. In contrast, unvaccinated batches had a high prevalence of IBV GI-11 strains (70%). These findings highlight widespread IBV circulation in Brazil with persistent viral presence in vaccinated birds and wild viruses in unvaccinated ones. Collectively, the data reveal a widespread presence of IBV in Brazil, characterized by prolonged viral persistence in vaccinated animals and the occurrence of wild viruses in both unvaccinated birds and those vaccinated against specific strains. It can be concluded from this study that there was a widespread occurrence of IBV in Brazil, providing long viral persistence in vaccinated animals, as well as the occurrence of wild virus in unvaccinated birds or birds vaccinated against individual strains.
传染性支气管炎病毒（IBV）对全球家禽业构成重大威胁，因此需要强有力的监测和疫苗接种策略。本研究旨在对巴西的IBV进行监测，评估潜在的疫苗病毒逃逸情况，并评估疫苗在接种疫苗的肉鸡中的持久性。使用RT-PCR对来自六个州100个鸡群的总共1000份气管拭子进行了分析。结果显示，91%的鸡群IBV检测呈阳性。检测到的毒株包括GI-1、GI-11和GI-23。值得注意的是，90%的批次接种了含有GI-1或GI-11谱系的疫苗。该研究揭示了在接种疫苗后第16天至32天之间，67个样本中存在疫苗持久性。相比之下，未接种疫苗的批次中IBV GI-11毒株的流行率很高（70%）。这些发现突出了IBV在巴西的广泛传播，接种疫苗的禽类中存在持续性病毒，未接种疫苗的禽类中存在野生病毒。总体而言，数据显示IBV在巴西广泛存在，其特征是在接种疫苗的动物中病毒持续存在时间延长，以及在未接种疫苗的禽类和针对特定毒株接种疫苗的禽类中都出现了野生病毒。从这项研究可以得出结论，IBV在巴西广泛存在，在接种疫苗的动物中病毒持续存在时间长，以及在未接种疫苗的禽类或针对个别毒株接种疫苗的禽类中出现野生病毒。
