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本文引用的文献

1
Association between the Obstructive Sleep Apnea and Cephalometric Parameters in Teenagers.青少年阻塞性睡眠呼吸暂停与头影测量参数之间的关联。
J Clin Med. 2023 Oct 30;12(21):6851. doi: 10.3390/jcm12216851.
2
Upper airway morphology in adults with positional obstructive sleep apnea.成人位置性阻塞性睡眠呼吸暂停患者的上气道形态。
Sleep Breath. 2024 Mar;28(1):193-201. doi: 10.1007/s11325-023-02879-0. Epub 2023 Jul 19.
3
Metrics of sleep apnea severity: beyond the apnea-hypopnea index.睡眠呼吸暂停严重程度的指标:超越呼吸暂停低通气指数。
Sleep. 2021 Jul 9;44(7). doi: 10.1093/sleep/zsab030.
4
Craniofacial morphology in patients with obstructive sleep apnea: cephalometric evaluation.阻塞性睡眠呼吸暂停患者的颅面形态:头影测量评估。
Braz J Otorhinolaryngol. 2022 Mar-Apr;88(2):228-234. doi: 10.1016/j.bjorl.2020.05.026. Epub 2020 Jul 18.
5
Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.基于文献的分析估计全球阻塞性睡眠呼吸暂停的患病率和负担。
Lancet Respir Med. 2019 Aug;7(8):687-698. doi: 10.1016/S2213-2600(19)30198-5. Epub 2019 Jul 9.
6
Imaging of adult obstructive sleep apnoea.成人阻塞性睡眠呼吸暂停的影像学
Eur J Radiol. 2018 May;102:176-187. doi: 10.1016/j.ejrad.2018.03.010. Epub 2018 Mar 13.
7
Nocturnal hypoxia in obese-related obstructive sleep apnea as a putative trigger of oxidative stress in pediatric NAFLD progression.肥胖相关阻塞性睡眠呼吸暂停中的夜间低氧血症作为儿童非酒精性脂肪性肝病进展中氧化应激的假定触发因素。
J Hepatol. 2016 Sep;65(3):470-2. doi: 10.1016/j.jhep.2016.05.042. Epub 2016 Aug 5.
8
Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.成人阻塞性睡眠呼吸暂停患者的颅面和上呼吸道形态:头影测量研究的系统评价和荟萃分析。
Sleep Med Rev. 2017 Feb;31:79-90. doi: 10.1016/j.smrv.2016.01.007. Epub 2016 Jan 30.
9
Validation of the STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea among Different Populations: A Systematic Review and Meta-Analysis.STOP-Bang问卷作为不同人群阻塞性睡眠呼吸暂停筛查工具的验证:一项系统评价和荟萃分析
PLoS One. 2015 Dec 14;10(12):e0143697. doi: 10.1371/journal.pone.0143697. eCollection 2015.
10
Importance of cephalographs in diagnosis of patients with sleep apnea.头影测量在睡眠呼吸暂停患者诊断中的重要性。
Contemp Clin Dent. 2015 Sep;6(Suppl 1):S221-6. doi: 10.4103/0976-237X.166827.

头影测量分析中颅面变量与阻塞性睡眠呼吸暂停(OSA)之间相互关系的综合分析

A Comprehensive Analysis of the Interrelationship Between Craniofacial Variables in Cephalometric Analysis and Obstructive Sleep Apnea (OSA).

作者信息

Tanellari Olja, Alushi Adela, Ghanim Sara, Balcos Carina, Cioloca Daniel Petru, Zetu Irina Nicoleta

机构信息

Department of Orthodontics, Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.

Department of Orthodontics, Faculty of Dental Medicine, University of Medicine, 1005 Tirana, Albania.

出版信息

J Clin Med. 2025 Mar 14;14(6):1963. doi: 10.3390/jcm14061963.

DOI:10.3390/jcm14061963
PMID:40142771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11942956/
Abstract

: Obstructive sleep apnea syndrome (OSAS) is a global condition usually associated with poor health. While common, it appears underdiagnosed due to repeated episodes of upper airway obstruction during the sleep cycle. It is accompanied by other health risks like cardiovascular issues and conditions. Identifying craniofacial characteristics linked to OSAS may enhance diagnostic precision and treatment planning. The aim of our study was to examine the relationship between cephalometric variables and OSAS and determine whether craniofacial features influence the syndrome's development and severity. : Thirty participants were split into two groups: 15 diagnosed with OSAS and 15 controls. Cephalometric evaluations were performed using standardized lateral imaging, with craniofacial, dental, and hyoid bone parameters assessed. Statistical analysis compared these variables between groups to identify significant differences. : OSAS patients exhibited significantly shorter maxillary and mandibular lengths, increased anterior facial height, and reduced posterior facial height compared to controls. Dental analysis revealed reduced interincisal angles and lower mandibular incisor positions in the OSAS group. The hyoid bone was positioned lower and more posteriorly in OSAS patients, with significant differences in its distance to the C3 vertebra and mandibular plane. Although the soft palate dimensions were larger in OSAS patients, the differences were not statistically significant. : OSAS is associated with distinct craniofacial features, including shorter maxillary and mandibular lengths, altered facial height proportions, and lower hyoid bone positioning. These findings suggest that craniofacial morphology plays a significant role in OSAS pathophysiology. Future studies hinting at three-dimensional imaging could provide deeper insights into these associations.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)是一种全球普遍存在的疾病,通常与健康状况不佳有关。虽然很常见,但由于睡眠周期中反复出现上呼吸道阻塞,该病似乎诊断不足。它还伴有心血管问题等其他健康风险。识别与OSAS相关的颅面特征可能会提高诊断准确性和治疗规划水平。我们研究的目的是检查头影测量变量与OSAS之间的关系,并确定颅面特征是否会影响该综合征的发生和严重程度。

30名参与者被分为两组:15名被诊断为OSAS,15名作为对照组。使用标准化的侧位成像进行头影测量评估,评估颅面、牙齿和舌骨参数。通过统计分析比较两组之间的这些变量,以确定显著差异。

与对照组相比,OSAS患者的上颌和下颌长度明显较短,面部前部高度增加,面部后部高度降低。牙齿分析显示,OSAS组的切牙间角度减小,下颌切牙位置较低。OSAS患者的舌骨位置更低且更靠后,其与C3椎体和下颌平面的距离存在显著差异。虽然OSAS患者的软腭尺寸更大,但差异无统计学意义。

OSAS与独特的颅面特征有关,包括上颌和下颌长度较短、面部高度比例改变以及舌骨位置较低。这些发现表明颅面形态在OSAS病理生理学中起重要作用。未来关于三维成像的研究可能会更深入地揭示这些关联。