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遵循盖兰-吉勒腰椎退行性脊椎滑脱分类治疗指南是否会影响手术结果?一项匹配-不匹配研究。

Does Adherence to Treatment Guidelines from the Ghailane-Gille Classification for Degenerative Spondylolisthesis of the Lumbar Spine Impact Surgical Outcomes? A Match-Mismatch Study.

作者信息

Soufiane Ghailane, Matthieu Campana, Olivier Gille, Houssam Bouloussa, Clément Jacquemin, Etienne Castelain Jean, Vincent Challier

机构信息

Department of Spinal Surgery Unit, Hôpital Privé Francheville, 24000 Périgueux, France.

Department of Spinal Surgery Unit 1, Université de Bordeaux, Bordeaux University Hospital, C.H.U. Tripode Pellegrin, Place Amélie Raba Léon, 33076 Bordeaux, France.

出版信息

J Clin Med. 2025 Mar 17;14(6):2041. doi: 10.3390/jcm14062041.

DOI:10.3390/jcm14062041
PMID:40142849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11943325/
Abstract

: satisfactory sagittal alignment when treating degenerative spondylolisthesis of the lumbar spine (DSLS) may produce better clinical and radiographic outcomes compared to treatment focused solely on isolated segments when indicated. Ghailane et al. proposed a treatment guideline based on their classification system. The aim of this study was to investigate the impact of adherence to Ghailane-Gille (GG) treatment guidelines on surgical outcomes in patients with DSLS. : A monocentric retrospective cohort analysis was performed from 2021 to September 2024. Data were collected from patients treated for DSLS, covering the period from baseline to one-year follow-up. Patients were divided into two groups based on GG treatment guidelines: the "Match group" (patients who underwent surgery following GG guidelines) and the "Mismatch group" (patients who did not adhere to these guidelines). Preoperative and postoperative clinical outcomes, patient satisfaction, and operative parameters were collected and compared between groups. : A total of 80 patients were enrolled, with 52 in the Match group and 28 in the Mismatch group. At baseline, the Oswestry Disability Index (ODI) score demonstrated significant variation among classification subtypes and a positive correlation. The Match group exhibited a significant reduction in ODI scores one year postoperatively and maintained high levels of satisfaction; no significant intraoperative differences were noted. Additionally, patients in the Mismatch group were more frequently classified as () III compared to the Match group (70% vs. 30%), suggesting clinicians' hesitance to fully implement GG guidelines in aggressive treatment strategies for those patients. : Adhering to the GG treatment guidelines for restoring sagittal alignment in DSLS patients is associated with decreased ODI scores regardless of age, ensuring patient satisfaction at one-year follow-up. This approach could potentially benefit ASA III patients as well.

摘要

与仅针对特定节段进行治疗相比,治疗腰椎退行性椎体滑脱(DSLS)时令人满意的矢状面排列可能会产生更好的临床和影像学结果。盖兰内等人基于他们的分类系统提出了一种治疗指南。本研究的目的是调查遵循盖兰内 - 吉勒(GG)治疗指南对DSLS患者手术结果的影响。:进行了一项单中心回顾性队列分析,时间跨度为2021年至2024年9月。收集了接受DSLS治疗患者的数据,涵盖从基线到一年随访的时间段。根据GG治疗指南将患者分为两组:“匹配组”(按照GG指南接受手术的患者)和“不匹配组”(未遵循这些指南的患者)。收集并比较两组患者术前和术后的临床结果、患者满意度以及手术参数。:共纳入80例患者,其中匹配组52例,不匹配组28例。在基线时,Oswestry功能障碍指数(ODI)评分在分类亚型之间显示出显著差异且呈正相关。匹配组术后一年ODI评分显著降低,并保持了较高的满意度;术中未发现显著差异。此外,与匹配组相比,不匹配组患者被更频繁地分类为()III级(70%对30%),这表明临床医生在对这些患者的积极治疗策略中对全面实施GG指南存在犹豫。:对于DSLS患者,遵循GG治疗指南恢复矢状面排列与ODI评分降低相关,无论年龄如何,并确保一年随访时患者满意度。这种方法可能对ASA III级患者也有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/1898836fdcc1/jcm-14-02041-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/991772e0c6af/jcm-14-02041-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/314e13fcd950/jcm-14-02041-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/1898836fdcc1/jcm-14-02041-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/991772e0c6af/jcm-14-02041-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/314e13fcd950/jcm-14-02041-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc68/11943325/1898836fdcc1/jcm-14-02041-g003.jpg

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本文引用的文献

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Radiographic and surgery-related predictive factors for increased segmental lumbar lordosis following lumbar fusion surgery in patients with degenerative lumbar spondylolisthesis.退变性腰椎滑脱症患者行腰椎融合术后增加节段性腰椎前凸的影像学和手术相关预测因素。
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Correction: Degenerative lumbar spondylolisthesis: review of current classifications and proposal of a novel classification system.
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