伴有软骨炎症的口腔和生殖器溃疡：MAGIC综合征。5例具有复发性多软骨炎和白塞病特征的患者。
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and Behçet's disease.
作者信息
Firestein G S, Gruber H E, Weisman M H, Zvaifler N J, Barber J, O'Duffy J D
出版信息
Am J Med. 1985 Jul;79(1):65-72. doi: 10.1016/0002-9343(85)90547-9.
PMID:4014306
Abstract
Five patients with features of coexistent relapsing polychondritis and Behçet's disease are described. Review of the literature supports the overlap of the clinical manifestations of these two conditions. A common immunologic abnormality is likely, and elastin is cited as a possible target antigen. The "mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome" is the proposed name for this entity.
摘要
本文描述了5例同时具有复发性多软骨炎和白塞病特征的患者。文献回顾支持这两种疾病临床表现存在重叠。可能存在共同的免疫异常，弹性蛋白被认为是一种可能的靶抗原。“伴有软骨炎症的口腔和生殖器溃疡（MAGIC）综合征”是为此实体提出的名称。
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