McLaughlin M K, Quinn P, Farnham J G
Am J Obstet Gynecol. 1985 Jul 1;152(5):593-8. doi: 10.1016/0002-9378(85)90634-9.
The data generated by this study are consistent with the fact that pregnancy and progesterone treatment are associated with an increase in vascular reactivity to phenylephrine and a decrease in reactivity to angiotensin II in the circulation to the hind limb of the ewe. This shows that the way in which vascular reactivity changes during pregnancy is dependent both upon the circulation and the vasoconstrictor being examined. It suggests that sensitivity and contractility could change in opposite directions in this circulation during pregnancy. This will require additional verification, both as to its existence and whether this is an important normal cardiovascular adaptation to pregnancy.
妊娠和孕酮治疗与母羊后肢循环中对去氧肾上腺素的血管反应性增加以及对血管紧张素II的反应性降低有关。这表明妊娠期间血管反应性变化的方式既取决于循环系统，也取决于所检测的血管收缩剂。这表明在妊娠期间，该循环系统中的敏感性和收缩性可能会朝相反方向变化。这一点无论是其存在与否，以及这是否是对妊娠的重要正常心血管适应性变化，都需要进一步验证。
