Chakrabarti Asmita, Kumari Shailaja, Maiti Moumita, DAS Chhanda, Barui Gopinath
Nil Ratan Sircar Medical College and Hospital.
Curr Health Sci J. 2024 Oct-Dec;50(5):599-606. doi: 10.12865/CHSJ.50.04.14. Epub 2024 Dec 31.
Germ cell tumors (GCTs) are heterogeneous group of neoplasms that arise from primordial germ cells and can occur in various locations, most commonly in the ovaries and testes but can also be found in extra-gonadal sites like retroperitoneum due to developmental errors. These tumors are relatively rare but clinically significant due to their potential for malignancy and association with developmental anomalies.
This case series presents four rare and unusual cases of germ cell tumors encountered in both paediatric and adult patients, each with distinctive clinical, radiological, and histopathological features. These cases are unique in their clinical presentation and histomorphological findings, reflecting the diverse spectrum of GCTs across different age groups.
These cases underscore the complexity of diagnosis, the role of radiological and histopathological examinations, and the varied management strategies for rare conditions like gonadoblastoma, dysgerminoma, struma ovarii, and fetus-in-fetu.
生殖细胞肿瘤（GCTs）是一组异质性肿瘤，起源于原始生殖细胞，可发生于多个部位，最常见于卵巢和睾丸，但也可因发育异常而在性腺外部位如腹膜后发现。这些肿瘤相对罕见，但因其潜在的恶性程度以及与发育异常的关联而具有临床意义。
本病例系列展示了在儿科和成年患者中遇到的4例罕见且不寻常的生殖细胞肿瘤病例，每例都具有独特的临床、放射学和组织病理学特征。这些病例在临床表现和组织形态学发现方面具有独特性，反映了不同年龄组GCTs的多样谱。
这些病例强调了诊断的复杂性、放射学和组织病理学检查的作用，以及对于诸如性腺母细胞瘤、无性细胞瘤、卵巢甲状腺肿和胎中胎等罕见病症的不同管理策略。
