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以急症形式出现的小儿坏死性红斑麻风

Pediatric Erythema Leprosum Necroticans Presenting as Emergency.

作者信息

Ahmed Ghazal, Chhabra Namrata, Chirayath Anju George, Choudhary Ritul

机构信息

Department of Dermatology, Venereology and Leprosy, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.

Department of Dermatology, Venereology and Leprosy, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

Curr Health Sci J. 2024 Oct-Dec;50(5):612-617. doi: 10.12865/CHSJ.50.04.16. Epub 2024 Dec 31.

DOI:10.12865/CHSJ.50.04.16
PMID:40143883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11936072/
Abstract

Lepromatous leprosy is considered rare in children owing to the immature immune system. Lepra reaction, although not uncommon, type-2 lepra reaction in childhood is scarcely reported. We report five such cases, all presented in our institutes' emergency department with severe type-2 lepra reaction as the presenting entity. They had multiple classical features of leprosy, like ulcero-necrotic lesions, deformity, neuritis, and high slit smear bacillary index, which are otherwise usual in adult leprosy and not seen in childhood leprosy. Childhood leprosy being an indicator of active transmission in the community, these cases are crucial from the rarity viewpoint but also a pointer of recrudescence in the post-elimination era, highlighting the need for more aggressive case detection and better active surveillance.

摘要

由于免疫系统不成熟,瘤型麻风在儿童中被认为较为罕见。麻风反应虽然并不少见,但儿童2型麻风反应的报道却很少。我们报告了5例此类病例,所有病例均在我们机构的急诊科就诊,以严重的2型麻风反应为首发症状。他们具有多种麻风的典型特征,如溃疡坏死性病变、畸形、神经炎和高涂片菌指数,这些特征在成人麻风病中较为常见,而在儿童麻风病中则未见。儿童麻风病是社区中疾病活跃传播的一个指标,从罕见性的角度来看,这些病例至关重要,同时也表明在消除麻风病之后的时代疾病有复发的迹象,凸显了更积极的病例发现和更好的主动监测的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/250a3cdf0489/CHSJ-50-04-612-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/30c2b06d2614/CHSJ-50-04-612-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/c3a46fbbe73c/CHSJ-50-04-612-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/e1954b1a996b/CHSJ-50-04-612-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/56ac9e92c6c0/CHSJ-50-04-612-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/250a3cdf0489/CHSJ-50-04-612-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/30c2b06d2614/CHSJ-50-04-612-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/c3a46fbbe73c/CHSJ-50-04-612-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/e1954b1a996b/CHSJ-50-04-612-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/56ac9e92c6c0/CHSJ-50-04-612-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9b2/11936072/250a3cdf0489/CHSJ-50-04-612-fig5.jpg

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