Hsu Chou-Yi, Hameed Ghusoon Faidhi, Ahmad Irfan, Kumar Abhinav, Ganesan Subbulakshmi, Shankhyan Aman, Sunitha S, Panigrahi Rajashree
Thunderbird School of Global Management, Arizona State University Tempe Campus Phoenix Arizona 85004 USA.
Department of Chemistry, College of Education, University of Al-Qadisiyah Iraq.
Nanoscale Adv. 2025 Mar 10;7(9):2663-2676. doi: 10.1039/d5na00168d. eCollection 2025 Apr 29.
A novel salicylamide-l-proline-nickel(ii) complex, supported on magnetic iron oxide [FeO@salicylamide-l-proline-Ni(ii)], was synthesized through a three-step procedure. This included the functionalization of FeO with amine groups using glycine as a linker, followed by direct amidation of salicylic acid and its subsequent coordination with Ni(ii) and l-proline as a co-ligand to form the nanomagnetic Ni(ii) complex. The resulting catalyst was comprehensively characterized by several techniques. The catalyst exhibited outstanding catalytic performance in the homoselective synthesis of 5-substituted-1-tetrazoles from benzonitriles. Notably, it demonstrated excellent recyclability, maintaining high efficiency over eight reaction cycles. The use of a low-cost linker, ligand, and complex catalyst, combined with easy magnetic separation, minimal leaching, and scalability, renders this approach both environmentally sustainable and economically advantageous compared to traditional Ni-based methods.
通过三步法合成了一种负载在磁性氧化铁上的新型水杨酰胺 - L - 脯氨酸 - 镍（II）配合物[FeO@水杨酰胺 - L - 脯氨酸 - Ni（II）]。这包括使用甘氨酸作为连接剂对FeO进行胺基官能化，随后将水杨酸直接酰胺化，及其随后与Ni（II）和L - 脯氨酸作为共配体配位以形成纳米磁性Ni（II）配合物。通过多种技术对所得催化剂进行了全面表征。该催化剂在由苯甲腈进行5 - 取代 - 1 - 四唑的均相选择性合成中表现出出色的催化性能。值得注意的是，它表现出优异的可回收性，在八个反应循环中保持高效率。与传统的镍基方法相比，使用低成本的连接剂、配体和复合催化剂，再加上易于磁分离、最小化浸出和可扩展性，使得这种方法在环境可持续性和经济优势方面都具有优势。
