Department of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, P.O. Box, Babolsar, 47416-95447, Iran.
Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.
Sci Rep. 2024 Sep 14;14(1):21488. doi: 10.1038/s41598-024-72212-6.
Graphite carbon nitride (g-CN) is a two-dimensional nano-sheet with electronic properties, which shows unique characteristics with high chemical and thermal stability in its structure. The functionalization of these compounds through covalent bonding is an important step towards significantly improving their properties and capabilities. To achieve this goal, a novel strategy for the covalent functionalization of FeO@g-CN with thiamine hydrochloride (vitamin B1) via cyanuric chloride (TCT), which is a divalent covalent linker, was presented. The efficiency of FeO@gCN@Thiamine as a heterogeneous organic catalyst in the synthesis of spirooxindole-pyran derivatives and 2-amino-4H-pyran under solvent-free conditions was evaluated and the yields of high-purity products were presented. In addition, easy recycling and reuse for seven consecutive cycles without significant reduction in catalytic activity are other features of this catalyst. Moreover, the performance of the prepared sorbent in the microextraction technique (herein, magnetic solid phase extraction) was studied. The tebuconazole was selected as the target analyte. The target analyte was extracted and determined by HPLC-UV. Under the optimum condition, the linear range of the method (LDR) was estimated in the range of 0.2-100 μg L (the coefficient of determination of 0.9962 for tebuconazole). The detection limit (LOD) of the method for tebuconazole was calculated to be 0.05 µg L. The limit of quantification (LOQ) of the method was also estimated to be 0.16 µg L. In order to check the precision of the proposed method, the intra-day and inter-day relative standard deviations (RSD%) were calculated, which were in the range of 1.5- 2.8%. The method was used for the successful extraction and determination of tebuconazole in tomato, cucumber, and carrot samples.
石墨相氮化碳（g-CN）是一种具有电子特性的二维纳米片，其结构具有高化学和热稳定性，表现出独特的特性。通过共价键对这些化合物进行功能化是显著改善其性能和能力的重要步骤。为了实现这一目标，提出了一种通过三聚氰胺氯（TCT），即二价共价连接体，用盐酸硫胺（维生素 B1）对 FeO@g-CN 进行共价功能化的新策略。在无溶剂条件下，评估了 FeO@gCN@Thiamine 作为一种杂相有机催化剂在合成螺噁吲哚-吡喃衍生物和 2-氨基-4H-吡喃中的效率，并提出了高纯度产物的产率。此外，该催化剂还具有易于回收和重复使用七次且催化活性无明显降低的特点。此外，还研究了制备的吸附剂在微萃取技术（此处为磁性固相萃取）中的性能。选择噻菌灵作为目标分析物。通过 HPLC-UV 对目标分析物进行提取和测定。在最佳条件下，该方法的线性范围（LDR）估计在 0.2-100μg L（噻菌灵的决定系数为 0.9962）范围内。该方法对噻菌灵的检测限（LOD）计算为 0.05μg L。该方法的定量限（LOQ）也估计为 0.16μg L。为了检查该方法的精密度，计算了日内和日间相对标准偏差（RSD%），其范围为 1.5-2.8%。该方法成功用于提取和测定番茄、黄瓜和胡萝卜样品中的噻菌灵。
