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孕期福勒氏综合征管理的病例报告:挑战与结果

Case Report of Management of Fowler's Syndrome During Pregnancy: Challenges and Outcomes.

作者信息

Rodrigues Rodrigo F, Antonini Marcelo, Toledo Maria Luiza, Silva Eliza K, Silva Hudson F

机构信息

Obstetrics and Gynaecology Department, Servidor Público Estadual Hospital - Francisco Morato Oliveira (HSPE-FMO), Sao Paulo, BRA.

Mastology Department, Servidor Público Estadual Hospital - Francisco Morato Oliveira (HSPE-FMO), Sao Paulo, BRA.

出版信息

Cureus. 2025 Feb 23;17(2):e79523. doi: 10.7759/cureus.79523. eCollection 2025 Feb.

Abstract

Fowler's syndrome (FS) is a rare cause of urinary retention affecting young women, characterized by dysfunctional urethral sphincter relaxation. Its management during pregnancy presents challenges, particularly regarding sacral neuromodulation (SNM), which is the preferred treatment but remains controversial due to concerns about uterine contractions and limited safety data. Intermittent catheterization is an alternative but increases the risk of urinary tract infections and pregnancy complications. This case report aims to describe the obstetric management and clinical outcomes of a pregnant patient with Fowler's syndrome undergoing SNM. A 25-year-old woman with FS conceived unexpectedly and, concerned about potential pregnancy risks, deactivated the device and initiated intermittent catheterization. However, she experienced persistent urinary retention, nocturia, and sciatic pain, prompting her to reactivate the device without medical supervision. Despite these challenges, her pregnancy progressed without urinary tract infections or preterm labor. At 37 weeks and four days, she underwent a planned cesarean section, delivering a healthy newborn. Managing FS during pregnancy is complex due to the risks and benefits of SNM versus intermittent catheterization. This case highlights the need for individualized, multidisciplinary care. Further research is essential to develop standardized guidelines to optimize maternal and fetal outcomes.

摘要

福勒综合征(FS)是导致年轻女性尿潴留的罕见病因,其特征为尿道括约肌松弛功能障碍。孕期对其进行管理存在挑战,尤其是骶神经调节(SNM)方面,这是首选治疗方法,但由于担心子宫收缩以及安全数据有限,该方法仍存在争议。间歇性导尿是一种替代方法,但会增加尿路感染和妊娠并发症的风险。本病例报告旨在描述一名患有福勒综合征的孕妇接受骶神经调节治疗的产科管理及临床结局。一名25岁患有福勒综合征的女性意外怀孕,因担心潜在的妊娠风险,停用了设备并开始进行间歇性导尿。然而,她持续存在尿潴留、夜尿症和坐骨神经痛,促使她在未经医学监督的情况下重新激活了设备。尽管面临这些挑战,她的妊娠过程中未发生尿路感染或早产。在孕37周零4天时,她接受了计划剖宫产,产下一名健康的新生儿。由于骶神经调节与间歇性导尿的风险和益处,孕期管理福勒综合征较为复杂。本病例凸显了个体化、多学科护理的必要性。进一步的研究对于制定标准化指南以优化母婴结局至关重要。

相似文献

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Chronic Urinary Retention due to Fowler's Syndrome.福勒氏综合征所致慢性尿潴留
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Fowler's syndrome and pregnancy.福勒氏综合征与妊娠
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本文引用的文献

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Safety of Sacral Nerve Stimulation in Pregnancy: A Literature Review.孕期骶神经刺激的安全性:文献综述
Neuromodulation. 2016 Oct;19(7):770-779. doi: 10.1111/ner.12450. Epub 2016 Jun 10.
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Fowler's syndrome and pregnancy.福勒氏综合征与妊娠
BMJ Case Rep. 2010 Sep 9;2010:bcr0520103032. doi: 10.1136/bcr.05.2010.3032.

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