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一名患有福勒综合征和逼尿肌过度活动症的患者在进行蛤蚌膀胱扩大术和米氏术式后怀孕

Pregnancy Following Clam Cystoplasty and Mitrofanoff Procedure in a Patient With Fowler's Syndrome and Detrusor Overactivity.

作者信息

Malik Humaira S, Saad Salma

机构信息

Department of Obstetrics and Gynecology, Dumfries and Galloway Royal Infirmary, Dumfries, GBR.

出版信息

Cureus. 2025 Aug 5;17(8):e89423. doi: 10.7759/cureus.89423. eCollection 2025 Aug.

DOI:10.7759/cureus.89423
PMID:40918795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12410504/
Abstract

Fowler's syndrome causes urinary retention due to failure of the urethral sphincter to relax. Management aims for complete bladder emptying, typically via intermittent self-catheterization. If conservative treatment fails, detrusor overactivity with Fowler's syndrome may be managed surgically using clam cystoplasty and the Mitrofanoff procedure to increase bladder capacity and reduce pressure. We report a rare case of pregnancy in a woman with Fowler's syndrome and detrusor overactivity, who previously underwent clam cystoplasty and Mitrofanoff procedure. She had a continent, functional abdominal stoma for clean intermittent catheterization. Her pregnancy was complicated by recurrent urinary tract infections and bladder spasms requiring antibiotics. A planned cesarean section was performed at 35 weeks following steroid administration and discussion with the multidisciplinary team, resulting in the delivery of a live baby. This case illustrates pregnancy management complexities in these women, focusing on the need for individualized, multidisciplinary care.

摘要

福勒氏综合征因尿道括约肌无法松弛而导致尿潴留。治疗目标是实现膀胱完全排空,通常通过间歇性自我导尿来完成。如果保守治疗失败,对于伴有福勒氏综合征的逼尿肌过度活动,可通过行膀胱扩大术和米氏术进行手术治疗,以增加膀胱容量并降低压力。我们报告了一例罕见病例,一名患有福勒氏综合征和逼尿肌过度活动的女性怀孕,她此前接受过膀胱扩大术和米氏术。她有一个可控的、用于清洁间歇性导尿的功能性腹部造口。她的孕期因反复尿路感染和膀胱痉挛而复杂化,需要使用抗生素。在给予类固醇并与多学科团队讨论后,于35周时进行了计划剖宫产,产下一名活婴。该病例说明了这些女性孕期管理的复杂性,强调了个体化多学科护理的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5081/12410504/408f46100236/cureus-0017-00000089423-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5081/12410504/408f46100236/cureus-0017-00000089423-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5081/12410504/408f46100236/cureus-0017-00000089423-i01.jpg

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本文引用的文献

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Case Report of Management of Fowler's Syndrome During Pregnancy: Challenges and Outcomes.孕期福勒氏综合征管理的病例报告:挑战与结果
Cureus. 2025 Feb 23;17(2):e79523. doi: 10.7759/cureus.79523. eCollection 2025 Feb.
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Augmentation cystoplasty in the patient with neurogenic bladder.神经源性膀胱患者的膀胱扩大术。
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Pregnancy following urinary tract reconstruction using bowel segments: a review of published literature.经肠道段尿路重建术后的妊娠:文献回顾。
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8
Management of pregnancy after augmentation cystoplasty.膀胱扩大成形术后的妊娠管理。
BMJ Case Rep. 2015 May 20;2015:bcr2015209304. doi: 10.1136/bcr-2015-209304.
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Fowler's syndrome and pregnancy.福勒氏综合征与妊娠
BMJ Case Rep. 2010 Sep 9;2010:bcr0520103032. doi: 10.1136/bcr.05.2010.3032.
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