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本文引用的文献

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BMC Pulm Med. 2024 Jan 27;24(1):57. doi: 10.1186/s12890-023-02813-w.
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Obesity exacerbates influenza-induced respiratory disease via the arachidonic acid-p38 MAPK pathway.肥胖通过花生四烯酸-p38丝裂原活化蛋白激酶途径加重流感诱导的呼吸道疾病。
Front Pharmacol. 2023 Aug 23;14:1248873. doi: 10.3389/fphar.2023.1248873. eCollection 2023.
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Association of body mass index and weight change with pneumonia mortality in a Japanese population: Japan Public Health Center-based Prospective Study.体重指数和体重变化与日本人群肺炎死亡率的关系:日本基于公共卫生中心的前瞻性研究。
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Effect of Undernutrition and Obesity on Clinical Outcomes in Adults with Community-Acquired Pneumonia.营养不良和肥胖对社区获得性肺炎成人临床结局的影响。
Nutrients. 2022 Aug 7;14(15):3235. doi: 10.3390/nu14153235.
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No obesity paradox in patients with community-acquired pneumonia - secondary analysis of a randomized controlled trial.社区获得性肺炎患者中无肥胖悖论 - 一项随机对照试验的二次分析。
Nutr Diabetes. 2022 Mar 23;12(1):12. doi: 10.1038/s41387-022-00190-7.
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Influence of overweight and obesity on the mortality of hospitalized patients with community-acquired pneumonia.超重和肥胖对社区获得性肺炎住院患者死亡率的影响。
World J Clin Cases. 2022 Jan 7;10(1):104-116. doi: 10.12998/wjcc.v10.i1.104.
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Obesity survival paradox in patients hospitalized with community-acquired pneumonia. Assessing sex-differences in a population-based cohort study.社区获得性肺炎住院患者的肥胖生存悖论。基于人群的队列研究评估性别差异。
Eur J Intern Med. 2022 Apr;98:98-104. doi: 10.1016/j.ejim.2022.01.027. Epub 2022 Jan 20.
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The menace of obesity to depression and anxiety prevalence.肥胖对抑郁症和焦虑症患病率的威胁。
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Association between body mass index and mortality in hospitalised patients with community-acquired pneumonia.社区获得性肺炎住院患者体重指数与死亡率之间的关联。
ERJ Open Res. 2021 Mar 22;7(1). doi: 10.1183/23120541.00736-2020. eCollection 2021 Jan.
10
The impact of obesity on seasonal influenza: a single-center, retrospective study conducted in Israel.肥胖对季节性流感的影响:以色列单中心回顾性研究。
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社区获得性肺炎患者中的肥胖悖论:你是否充分考虑了混杂因素?

Obesity paradox in patients with community-acquired pneumonia: Have you fully considered the confounding factors?

作者信息

Sun Jin-Ke, Tian Hui

机构信息

Department of Pulmonary and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong Province, China.

Department of Critical Care Medicine, Liaocheng People's Hospital, Liaocheng 252000, Shandong Province, China.

出版信息

World J Clin Cases. 2025 Mar 26;13(9):97915. doi: 10.12998/wjcc.v13.i9.97915.

DOI:10.12998/wjcc.v13.i9.97915
PMID:40144481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11670021/
Abstract

There exists a notion that there is an obesity paradox in the prognosis of community-acquired pneumonia. In other words, obese individuals with community-acquired pneumonia have a better prognosis. The study by Wang supports this claim, but we believe that the obesity paradox should not be proposed hastily as it is influenced by numerous subjective and objective confounding factors.

摘要

有一种观点认为,社区获得性肺炎的预后存在肥胖悖论。换句话说,患有社区获得性肺炎的肥胖个体预后较好。王的研究支持了这一说法,但我们认为,肥胖悖论不应仓促提出,因为它受到众多主观和客观混杂因素的影响。