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头部CT成像中解剖学和基于适应症的诊断参考水平(DRLs)比较:对辐射剂量管理的影响

Comparison of Anatomical and Indication-Based Diagnostic Reference Levels (DRLs) in Head CT Imaging: Implications for Radiation Dose Management.

作者信息

Ohene-Botwe Benard, Anim-Sampong Samuel, Saizi Robert

机构信息

Department of Midwifery and Radiography, School of Health & Psychological Sciences, City, University of London, London, UK.

Department of Radiography, University of Ghana, Accra, Ghana.

出版信息

Int J Biomed Imaging. 2025 Mar 19;2025:6464273. doi: 10.1155/ijbi/6464273. eCollection 2025.

Abstract

Many diagnostic reference levels (DRLs) in computed tomography (CT) imaging are based mainly on anatomical locations and often overlook variations in radiation exposure due to different clinical indications. While indication-based DRLs, derived from dose descriptors like volume-weighted CT dose index (CTDI) and dose length product (DLP), are recommended for optimising patient radiation exposure, many studies still use anatomical-based DRL values. This study is aimed at quantifying the differences between anatomical and indication-based DRL values in head CT imaging and assessing its implications for radiation dose management. This will support the narrative when explaining the distinction between indication-based DRLs and anatomical DRLs for patients' dose management. Employing a retrospective quantitative study design, we developed and compared anatomical and common indication-based DRL values using a dataset of head CT scans with similar characteristics. The indications included in the study were brain tumor/intracranial space-occupying lesion (ISOL), head injury/trauma, stroke, and anatomical examinations. Data analysis was conducted using SPSS Version 29. The findings suggest that using anatomical-based DLP DRL values for CT head examinations leads to underestimations in the median, 25th percentile, and 75th percentile values of head injury/trauma by 20.2%, 30.0%, and 14.5% in single-phase CT head procedures. Conversely, for the entire examination, using anatomical-based DLP DRL as a benchmark for CT stroke DRL overestimates median, 25th percentile, and 75th percentile values by 18.3%, 23.9%, and 13.5%. Brain tumor/ISOL DL values are underestimated by 62.6%, 60.4%, and 71.8%, respectively. The study highlights that using anatomical DLP DRL values for specific indications in head CT scans can lead to underestimated or overestimated DL values, making them less reliable for radiation management compared to indication-based DRLs. Therefore, it is imperative to promote the establishment and use of indication-based DRLs for more accurate dose management in CT imaging.

摘要

计算机断层扫描(CT)成像中的许多诊断参考水平(DRLs)主要基于解剖位置,并且常常忽略由于不同临床指征导致的辐射暴露差异。虽然基于临床指征的DRLs(从诸如体积加权CT剂量指数(CTDI)和剂量长度乘积(DLP)等剂量描述符推导得出)被推荐用于优化患者的辐射暴露,但许多研究仍使用基于解剖结构的DRL值。本研究旨在量化头部CT成像中基于解剖结构和基于临床指征的DRL值之间的差异,并评估其对辐射剂量管理的影响。这将有助于在向患者解释基于临床指征的DRLs和基于解剖结构的DRLs在剂量管理方面的区别时提供依据。采用回顾性定量研究设计,我们使用具有相似特征的头部CT扫描数据集,开发并比较了基于解剖结构和基于常见临床指征的DRL值。本研究纳入的临床指征包括脑肿瘤/颅内占位性病变(ISOL)、头部损伤/创伤、中风以及解剖学检查。使用SPSS 29版进行数据分析。研究结果表明,在单相CT头部检查中,使用基于解剖结构的DLP DRL值进行头部CT检查会导致头部损伤/创伤的中位数、第25百分位数和第75百分位数的值分别低估20.2%、30.0%和14.5%。相反,对于整个检查而言,将基于解剖结构的DLP DRL用作CT中风DRL的基准会使中位数、第25百分位数和第75百分位数的值分别高估18.3%、23.9%和13.5%。脑肿瘤/ISOL的DL值分别低估了62.6%、60.4%和71.8%。该研究强调,在头部CT扫描中针对特定临床指征使用基于解剖结构的DLP DRL值可能会导致DL值被低估或高估,与基于临床指征的DRLs相比,使其在辐射管理方面的可靠性较低。因此,必须推动建立和使用基于临床指征的DRLs,以便在CT成像中进行更准确的剂量管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45a/11944678/2d1dbc4d9c47/IJBI2025-6464273.001.jpg

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