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病例报告:骨扫描在检测里宾病中的作用。

Case Report: The role of bone scans in detecting Ribbing disease.

作者信息

Dambrain Abel, Bouron Clément, Lacoeuille Franck

机构信息

Department of Nuclear Medicine, University Hospital Center, Angers, France.

CRCI2NA-Inserm UMR1307/CNRS UMR 6075, University of Angers, Angers, France.

出版信息

Front Nucl Med. 2025 Mar 12;5:1527159. doi: 10.3389/fnume.2025.1527159. eCollection 2025.

DOI:10.3389/fnume.2025.1527159
PMID:40144686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11936802/
Abstract

In this case, we report the usefulness of bone scintigraphy in evaluating osteoarticular pain when the diagnosis is unclear after standard morphological imaging. A 24-year-old male patient exhibited mild left tibial pain that had been intensifying over a period of 2 years. The initial radiological evaluation suggested a diagnosis of pediatric tibial bone marrow osteosclerosis associated with periostitis, based on standard radiographs and MRI. However, a complementary bone scan was required for confirmation and showed moderate hyperemia and severe hyperfixation of the tibial lesion along with similar lesions on the left femur, both humeri, and the right ulna. These new findings led to a diagnosis of Ribbing disease, a rare sclerosing bone dysplasia.

摘要

在这种情况下,我们报告了骨闪烁显像在评估骨关节炎疼痛方面的有用性,此时标准形态学成像后诊断仍不明确。一名24岁男性患者出现轻度左胫骨疼痛,持续2年且逐渐加重。基于标准X线片和MRI,初步影像学评估提示诊断为小儿胫骨骨髓骨硬化合并骨膜炎。然而,需要进行补充骨扫描以确诊,结果显示胫骨病变有中度充血和重度放射性浓聚,左股骨、双侧肱骨及右尺骨也有类似病变。这些新发现导致诊断为里宾病,一种罕见的硬化性骨发育异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e87/11936802/b554bd3dc2f1/fnume-05-1527159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e87/11936802/418d7b1f0c11/fnume-05-1527159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e87/11936802/b554bd3dc2f1/fnume-05-1527159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e87/11936802/418d7b1f0c11/fnume-05-1527159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e87/11936802/b554bd3dc2f1/fnume-05-1527159-g002.jpg

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本文引用的文献

1
Sclerosing bone dysplasias: a pictorial essay.骨硬化发育异常:图文综述
Radiol Bras. 2025 Jan 6;57:e20240058. doi: 10.1590/0100-3984.2024.0058-en. eCollection 2024 Jan-Dec.
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Ribbing disease of tibia: a rare entity.胫骨肋状病:一种罕见的疾病。
BMJ Case Rep. 2021 Oct 28;14(10):e244868. doi: 10.1136/bcr-2021-244868.
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A Rare Case of Ribbing Disease- Diagnosis and Management.一例罕见的里宾病——诊断与治疗
J Orthop Case Rep. 2020 Jul;10(4):69-73. doi: 10.13107/jocr.2020.v10.i04.1808.
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Camurati-Engelmann Disease.卡姆鲁蒂-恩格尔曼病。
Calcif Tissue Int. 2019 May;104(5):554-560. doi: 10.1007/s00223-019-00532-1. Epub 2019 Feb 5.
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Validation of MRI classification system for tibial stress injuries.胫骨应力性损伤 MRI 分类系统的验证。
AJR Am J Roentgenol. 2012 Apr;198(4):878-84. doi: 10.2214/AJR.11.6826.
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Sclerosing bone dysplasias: review and differentiation from other causes of osteosclerosis.硬化性骨发育不良:综述及与其他骨质硬化病因的鉴别。
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Ribbing disease.里宾病
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Hereditary, multiple, diaphyseal sclerosis.遗传性多发性骨干硬化症
Acta Radiol (Stockh). 1949 Jun 30;31(5-6):522-36. doi: 10.3109/00016924909138232.