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10小时供体心脏缺血时间,采用10℃静态保存。

Ten hour donor heart ischemic time with 10ºC static storage.

作者信息

Tucker William, Patel Yatrik, Petrovic Mark, Schwartz Chris, Petree Brandon, Devries Steve, Lima Brian, Trahanas John, Bacchetta Matthew, Shah Ashish, Bommareddi Swaroop

机构信息

Vanderbilt University Medical Center, Department of Cardiac Surgery, Nashville, Tennessee.

Vanderbilt University Medical Center, Office of Transplant Procurement and Preservation, Nashville, Tennessee.

出版信息

JHLT Open. 2024 Oct 13;7:100163. doi: 10.1016/j.jhlto.2024.100163. eCollection 2025 Feb.

Abstract

Utilization of 10ºC static storage safely extended both ischemic time and travel radius in heart transplantation. A 57-year-old man with ischemic cardiomyopathy, a left ventricular assist device (LVAD), and end-stage renal disease was listed for combined heart-kidney transplant. The donor hospital in Anchorage, AK, was located approximately 2,700 nautical miles and 8 hours from the recipient center. The organ was transported in 10ºC static storage with over 10 hours of ischemic time and had superb early allograft function. Excellent outcomes with extended ischemic times can be achieved without machine perfusion, provided good recovery, storage, and implant techniques are followed.

摘要

在心脏移植中,使用10摄氏度静态保存可安全地延长缺血时间和扩大运输半径。一名57岁患有缺血性心肌病、植入左心室辅助装置(LVAD)且处于终末期肾病的男性被列入心脏-肾脏联合移植名单。位于阿拉斯加安克雷奇的供体医院距离受体中心约2700海里,行程8小时。该器官在10摄氏度静态保存下运输,缺血时间超过10小时,早期移植器官功能极佳。如果遵循良好的恢复、保存和植入技术,不使用机器灌注也可实现延长缺血时间后的良好结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c02/11935433/e753809ffbcc/gr1.jpg

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