Barnes Ashley, Broderick Kristen, Bush Errol, Orens Jonathan, Marashly Melanie, Shoham Shmuel, Avery Robin
Division of Infectious Disease, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
JHLT Open. 2024 Dec 8;7:100194. doi: 10.1016/j.jhlto.2024.100194. eCollection 2025 Feb.
This report details the case of a lung transplant recipient with a remote history of breast cancer and breast reconstruction with implants, who received lengthy antifungal therapy for a post-transplant donor-transmitted empyema. Despite this, she presented months later with a progressive infection of bilateral breast implants, which also proved to be due to . Few cases of breast implant infection after lung transplant have been published. It is possible that biofilm created a barrier to penetration of antifungals, which were able to suppress but not eradicate infection. This case highlights the importance of deep operative cultures for diagnosis and management of infections of this type.
本报告详细介绍了一例肺移植受者的病例，该受者有乳腺癌及乳房植入物重建的既往史，因移植后供体传播的脓胸接受了长时间的抗真菌治疗。尽管如此，数月后她出现双侧乳房植入物进行性感染，结果也证实是由……引起的。肺移植后乳房植入物感染的病例鲜有报道。生物膜可能形成了一道屏障，阻碍抗真菌药物的渗透，这些药物能够抑制但无法根除感染。该病例凸显了深部手术培养对于此类感染的诊断和管理的重要性。
